Research paperThe effects of renin-angiotensin system inhibition on aortic cholesterol content in cholesterol-fed rabbits
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Angiotensin converting enzyme (ACE) inhibitory, antihypertensive and antihyperlipidaemic activities of protein hydrolysates from Rhopilema esculentum
2012, Food ChemistryCitation Excerpt :Epidemiological and experimental studies have shown that ACE inhibitors had a beneficial effect in early atherosclerosis in addition to their antihypertensive activity (Chobanian, Haudenschild, Nickerson, & Drago, 1990; Fennessy, Campbell, & Campbell, 1994). Pharmacological studies have also demonstrated that ACE inhibitors could reduce plasma cholesterol in different animal models (Kowala, Grove, & Aberg, 1994; Sugano, Makino, & Yanaga, 1996). More recent studies have reported that protein hydrolysates from several food materials, such as sardinelle (Khaled et al., 2012), fish (Wergedahl, Gudbrandsen, Røst, & Berge, 2009), sesame (Biswas, Dhar, & Ghosh, 2010) and soy (Aoyama, Fukui, Takamatsu, Hashimoto, & Yamamoto, 2000; Zhong, Zhang, Ma, & Shoemaker, 2007) could affect plasma cholesterol concentrations and metabolisms of polyunsaturated fatty acids.
Inhibition of the renin-angiotensin system ameliorates genetically determined hyperinsulinemia
2002, European Journal of PharmacologyAttenuation of tissue P-selectin and MCP-1 expression and intimal proliferation by AT<inf>1</inf> receptor blockade in hyperlipidemic rabbits
2001, Biochemical and Biophysical Research Communications