Identification of nonsteroidal antiinflammatory drug-induced gastroduodenal injury in children with juvenile rheumatoid arthritis†
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Cited by (70)
Gastritis, Gastropathy, and Ulcer Disease
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2015, Textbook of Pediatric RheumatologyHepatic abscess following NSAID use in an adolescent
2014, Journal of Pediatric Surgery Case ReportsCitation Excerpt :Keenan et al. [4] reported a low incidence (0.7%) of gastropathy in children with juvenile rheumatoid arthritis (JRA) treated with NSAIDs, though other studies have reported a high prevalence of PUD in children taking aspirin and NSAIDs [5]. In fact, Mulberg et al. [6] reported in a cohort of children with RA treated with NSAIDs and referred for gastrointestinal complaints, more than 75% had gastritis, antral erosions, or ulcers. Even a single dose of NSAID could have toxic side effects, as Berezin et al. [7] described 4 children who were hospitalized for gastrointestinal bleeding after receiving only 1–2 doses of ibuprofen; all had a gastric ulcer visualized with EGD.
Peptic Ulcer and Other Conditions of the Stomach
2012, Pediatric Surgery, 2-Volume Set: Expert Consult - Online and PrintPeptic Ulcer and Other Conditions of the Stomach
2012, Pediatric SurgeryGastritis, Gastropathy, and Ulcer Disease
2011, Pediatric Gastrointestinal and Liver Disease
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Supported in part by the New England Medical Center/National Institutes of Health Digestive Disease Core Center (Center for Gastroenterology Research for Absorptive and Secretory Processes, grant P30 DK 34928), by National Institutes of Health Pediatric Gastroenterology Research Training Grant (T 32 DK 07471), by the Affiliated Children's Arthritis Centers of New England, Bureau of Maternal and Child Health (grant MCJ 255064), and by a Physician Scientist Award (K11 DK 02077-01) from the National Institutes of Health (awarded to Dr. Mulberg).
Presented in part at the annual meeting of the American Gastroenterological Association, San Francisco, Calif., May 1992 (published in abstract form, Gastroenterology 1992;102:A22).