Kawasaki disease in infants less than one year of age☆,☆☆,★
Section snippets
METHODS
We performed a retrospective chart review of patients less than 1 year of age at the onset of KD diagnosed at Children's Memorial Hospital (CMH), Chicago, from 1980 to 1993 inclusive. Demographic, clinical, laboratory, echocardiographic, therapeutic, and follow-up data were extracted from each medical record. Typical KD was diagnosed by the presence of fever for 5 or more days with at least four of five criteria,1 or fever plus three major criteria if CAA were recognized by echocardiography.4
RESULTS
Fifty-seven patients less than 1 year of age at the on set of KD were identified by medical record search and review of records of the division of infectious diseases. Three patients were lost to follow-up shortly after their acute illness, and one medical record was unavailable; data from the remaining 53 patients were analyzed. The 57 patients represent 13% of the total number of 443 patients with KD who were cared for at CMH during this period. No patients with known cardiac complications
DISCUSSION
This retrospective review of KD in infants less than 1 year of age extends information reported in non-age-restricted reports9 and in the few articles limited to this particular age group.3, 10, 11 We arbitrarily divided our patients into those <6 months and those >6 months of age to be consistant with previous reports.3, 10, 11 We failed to identify risk factors that predicted development of CAA in this population. Young age at the onset of KD, however, predicted the development of CAA in that
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From the Department of Pediatrics, Northwestern University Medical School, Division of Infectious Diseases, Children's Memorial Hospital, Chicago, Illinois
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Reprint requests: Elaine A. Rosenfeld, MD, Children's Memorial Hospital, Division of Infectious Diseases, 2300 Children's Plaza, Box No. 20, Chicago, IL 60614.
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0022-3476/95/$3.00 + 0 9/20/61437