Necrotizing Soft-Tissue Infections

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Practicing surgeons encounter a variety of soft-tissue infections, most of them minor. However, some patients with necrotizing soft-tissue sepsis initially may have minimal symptoms, masking a severe deep infection. Treatment includes broad spectrum antibiotics, early surgical debridement of all necrotic tissue, and a planned second-look operation. A high index of suspicion is necessary to minimize morbidity and mortality.

REFERENCES (75)

  • D.B. Roberts et al.

    Progressive synergistic bacterial gangrene arising from abscesses of the vulva and Bartholin’s gland duct

    Am J Obstet Gynecol

    (1972)
  • R.A. Scott et al.

    Phycomycosis of the vulva

    Am J Obstet Gynecol

    (1985)
  • D.V. Seal et al.

    Necrotizing fasciitis—a disease of temperate and warm climates

    Trans Roy Soc Trop Med Hyg

    (1982)
  • W.A. Addison et al.

    Necrotizing fasciitis of vulvar origin in diabetic patients

    Obstet Gynecol

    (1984)
  • M.F. Adinolfi et al.

    Severe systemic sepsis resulting from neglected perineal infections

    South Med J

    (1983)
  • Ahrenholz DH, Simmons RL: Mixed and synergistic infections. In Howard RJ, Simmons RL (eds): Surgical Infectious...
  • W. Altemeier et al.

    Prevention and treatment of gas gangrene

    JAMA

    (1971)
  • N.L. Ascher et al.

    Indium-111 autologous tagged leukocytes in the diagnosis of intraperitoneal sepsis

    Arch Surg

    (1979)
  • A. Barzilai et al.

    Necrotizing fasciitis: early awareness and principles of treatment

    Isr J Med Sci

    (1985)
  • A. Berg et al.

    Fournier’s gangrene complicating aggressive therapy for hematologic malignancy

    Cancer

    (1986)
  • A.N. Bessman et al.

    Nonclostridial gas gangrene

    JAMA

    (1975)
  • D.S. de Jongh et al.

    Postoperative synergistic gangrene

    JAMA

    (1967)
  • E.P. Dellinger

    Severe necrotizing soft-tissue infections: multiple disease entities requiring a common approach

    JAMA

    (1981)
  • M.F. Earle et al.

    Perirectal infections in patients with small cell lung cancer

    JAMA

    (1981)
  • J.R. Fisher et al.

    Necrotizing fasciitis: importance of roentgenographic studies for soft-tissue gas

    JAMA

    (1979)
  • A.J. Fournier

    Clinical study of fulminating gangrene of the penis

    Sem Medicale

    (1884)
  • W. Furste et al.

    Gangrenous soft tissue infections

    Infect Surg

    (1985)
  • D.L. Galbut et al.

    Spontaneous necrotizing fasciitis: occurrence secondary to occult diverticulitis

    JAMA

    (1977)
  • W. Gibboney et al.

    Necrotizing fasciitis of the scalp in neonates

    Am J Perinatol

    (1986)
  • G.N. Goldberg et al.

    Necrotizing fasciitis in infancy: report of three cases and review of the literature

    Pediatr Dermatol

    (1984)
  • G. Gorbach et al.

    Isolation of Clostridium in human infections: evaluation of 114 cases

    J Infect Dis

    (1975)
  • D. Gozal et al.

    Necrotizing fasciitis

    Arch Surg

    (1986)
  • G.B. Hart et al.

    Gas gangrene: a collective review

    J Trauma

    (1983)
  • D.M. Heimbach et al.

    Toxic epidermal necrolysis: a step forward in treatment

    JAMA

    (1987)
  • L.T. Hibbard et al.

    Subgluteal and retropsoal infection in obstetric practice

    Obstet Gynecol

    (1972)
  • R.J. Howard et al.

    Necrotizing soft-tissue infections caused by marine vibrios

    Surgery

    (1985)
  • J.M. Jacobson et al.

    Necrotizing fasciitis complicating intravenous lrug abuse

    Arch Intern Med

    (1982)

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    Department of Surgery, St. Paul–Ramsey Medical Center, 640 Jackson Street, St. Paul, Minnesota 55101

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