The diffuse endocrine system: from embryogenesis to carcinogenesis
6 References (524)
- et al.
Endothelin content of bronchoalveolar lavage fluid from allotransplanted pigs is increased during unmodified rejection
J. Thorac. Cardiovasc. Surg.
(1994) - et al.
Evidence for nitric oxide production by enterochromaffinlike cells in rat stomach under hypergastrinemia induced by proton pump inhibitors
Gastroenterology
(1995) - et al.
Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons
Cell
(1988) - et al.
Expression and motor effects of secretin in small and large intestine of the rat
Peptides
(2000) - et al.
Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas
Curr. Biol.
(1997) - et al.
Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin
Gastroenterology
(2001) - et al.
Neurogenic origin of human prostate endocrine cells
Urology
(1999) - et al.
Search for a physiological role of substance P in gastrointestinal motility
Neuroscience
(1985) - et al.
Synaptophysin immunoreactivity and small clear vesicles in neuroendocrine cells and related tumours
Mol. Cell. Probes.
(1987) - et al.
Occurrence, distribution and ontogeny of CGRP immunoreactivity in the rat lower respiratory tract: effect of capsaicin treatment and surgical denervations
Neuroscience.
(1986)
p27: a potential main inhibitor of cell proliferation in digestive endocrine tumors but not a marker of benign behavior
Hum. Pathol.
The neuroendocrine cell population of the human prostate gland
J. Urol.
Secretory granule content proteins and the luminal domains of granule membrane proteins aggregate in vitro at mildly acidic pH
J. biol. Chem.
The neuropeptide calcitonin gene-related peptide differently modulates proliferation and differentiation of smooth muscle cells in culture depending on the cell type
Regul. Pept.
N- and C-terminal domains direct cell type-specific sorting of chromogranin A to secretory granules
J. Biol. Chem.
Plasma neuroendocrine markers in patients with benign prostatic hyperplasia and prostatic carcinoma
J. Urol.
Sorting of the vasopressin prohormone into the regulated secretory pathway
FEBS. Lett.
The multiple endocrine neoplasia type I gene locus is involved in the pathogenesis of type II gastric carcinoids
Gastroenterology
Growth inhibition of human prostatic carcinoma cell lines by serotonin antagonists
Anticancer Res.
Neuroendocrine differentiation in prostatic carcinoma
Prostate
Calcitonin and calcitonin gene-related peptide in the human prostate gland
Prostate
Effects of substance P and calcitonin gene-related peptide on the pulmonary circulation
J. Appl. Physiol.
Pulmonary intraepithelial vagal nodose afferent nerve terminals are confined to neuroepithelial bodies: an anterograde tracing and confocal microscopy study in adult rats
Cell Tissue Res
Pulmonary neuroendocrine cells in tobacco-related lung disorders
Anat. Rec.
Increased pulmonary neuroendocrine cells with bombesin-like immunoreactivity in adult patients with eosinophilic granuloma
J. Clin. Invest.
Regulation of lung branching morphogenesis by bombesin-like peptides and neutral endopeptidase
Am. J. Respir. Cell. Mol. Biol.
Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
Genes Dev.
Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells
Nature
Immunohistochemical studies indicate multiple enteroendocrine cell differentiation pathways in the mouse proximal small intestine
Dev. Dyn.
Activated enterochromaffin like cell produces nitric oxide in the regenerative tissue of gastric ulcer and under hypergastrinemia
Gastroenterology
Leu-enkephalin-like material in nerves and enterochromaffin cells in the gut. An immunohistochemical study
Histochemistry
Classification of small cell lung cancer and pulmonary carcinoid by gene expression profiles
Cancer Res.
Further evidence that enterochromaffin cells are not derived from the neural crest
J. Embryol. Exp. Morphol.
The origin of gut and pancreatic neuroendocrine (APUD) cells-the last word?
J. Pathol.
Use of neuroendocrine serum markers in the follow-up of patients with cancer of the prostate
Prostate
Notch signalling controls pancreatic cell differentiation
Nature
Characterization of neuroendocrine differentiation in human benign prostate and prostatic adenocarcinoma
Cancer
Neuroendocrine differentiation and the bombesin/gastrin-releasing peptide family of neuropeptides in the progression of human prostate cancer
Prostate Suppl.
Somatostatin: abundance of immunoreactive hormone in rat stomach and pancreas
Science
Morphologic and regulatory aspects of prostatic function
Anat. Embryol. (Berl)
Localization of protein gene product 9.5 immunoreactivity in derivatives of the human Wolffian duct and in prostate cancer
Prostate
Mapping the distribution of neuroepithelial bodies of the rat lung. A whole-mount immunohistochemical approach
Am. J. Pathol.
The neural crest: its relations with APUD and paraneuron concepts
Arch. Histol. Jpn.
Involvement of BCL-2 oncoprotein in the development of enterochromaffin-like cell gastric carcinoids
Am. J. Surg. Pathol.
The stomach is a source of leptin
Nature
Localization of serotonin, cholecystokinin and somatostatin immunoreactivity in the lower respiratory tract of embryonic, foetal and postnatal sheep
Histol. Histopathol.
Coexistence of serotonin and cholecystokinin in paraneurons of the foetal sheep lung
Histol. Histopathol.
Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMP
The mechanism of pancreatic secretion
J. Pysiol. (Lond.)
Morphological support for paracrine inhibition of gastric acid secretion by nitric oxide in humans
Scand. J. Gastroenterol.
Cited by (38)
A Guide to Pheochromocytomas and Paragangliomas
2019, Surgical Pathology ClinicsCitation Excerpt :Supporting sustentacular cells help in maintaining the lobular structures, which are in turn surrounded by a prominent capillary network made up of pericytes, endothelial cells, and Schwann cells. The chromaffin/chief cells belong to the diffuse neuroendocrine system, discrete aggregates of neuroendocrine cells scattered throughout the body, and contain secretory granules and enzymes involved in catecholamine synthesis.7 The updated 2017 World Health Organization (WHO) Classification of Tumors of Endocrine Organs has incorporated new definitions, recent scientific advances, and novel genetic discoveries into the sections dedicated to PPGL.
Development of the Drosophila entero-endocrine lineage and its specification by the Notch signaling pathway
2011, Developmental BiologyCitation Excerpt :These cells, which typically outnumber cells of all other endocrine organs combined, represent the diffuse endocrine system (DES). Entero-endocrine cells produce different peptide hormones with specific regional distributions and functions (for review, see Rehfeld, 1998; Montuenga et al., 2003; Rindi et al., 2004). Well known examples from vertebrates are secretin or CKK (produced in the duodenum; stimulates pancreatic bicarbonate secretion), or gastrin (produced in the stomach; increases acid secretion from parietal cells).
Conserved genetic pathways controlling the development of the diffuse endocrine system in vertebrates and Drosophila
2010, General and Comparative EndocrinologyCitation Excerpt :These cells, which outnumber all other endocrine organs by a wide margin, form the diffuse endocrine system (DES). Within the DES, at least 14 different cell types have been identified which produce many different peptide hormones with a specific regional distribution (for review, see Rehfeld, 1998; Montuenga et al., 2003; Rindi et al., 2004). For example, secretin, produced in the duodenum, was one of the first hormones discovered and characterized around the turn of the 20th century (reviewed in Modlin et al., 2006); released by gastric acid, secretin stimulates secretion of bicarbonate-rich pancreatic juice.
UCHL1 (PGP 9.5): Neuronal biomarker and ubiquitin system protein
2010, Progress in NeurobiologyPoorly differentiated large cell endocrine carcinoma of the extrahepatic bile ducts
2009, Gastroenterologie Clinique et BiologiqueNeuroendocrine tumours of the chest area
2010, Polski Przeglad Chirurgiczny/ Polish Journal of Surgery