Adult urologyFluorescence photodetection of neoplastic urothelial lesions following intravesical instillation of 5-aminolevulinic acid*
References (21)
- et al.
Non-invasive papillary carcinoma of the bladder associated with carcinoma in situ
J Urol
(1976) - et al.
Superficial bladder cancer progression and recurrence
J Urol
(1983) - et al.
Detection of early lung cancer using low dose Photofrin II
Chest
(1990) - et al.
Predictability of recurrent and progressive disease in individual patients with primary superficial bladder cancer
J Urol
(1993) - et al.
Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience
J Photochem Photobiol B
(1990) - et al.
Prognostic significance of biopsy results of normal looking mucosa in a case of superficial bladder cancer
Br J Urol
(1983) - et al.
The significance of bladder quadrant biopsies in patients with primary superficial bladder carcinoma
Eur Urol
(1989) - et al.
Global status of clinical photodynamic therapy: the registration process for a new therapy
Lasers Surg Med
(1992) - et al.
Photodynamic diagnosis (PDD) of early stage malignancies—preliminary results in urology and pneumology
- et al.
Photodetection and photodynamic therapy of early squamous cell carcinomas of the pharynx exophagus and tracheobronchial tree
Lasers Med Sci
(1990)
Cited by (264)
Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (3rd report): Cost impact of transurethral resection of bladder tumor in Japan
2023, Photodiagnosis and Photodynamic TherapyAdvances in 5-aminoketovaleric acid(5-ALA) nanoparticle delivery system based on cancer photodynamic therapy
2022, Journal of Drug Delivery Science and TechnologyIdentification and pharmacological modification of resistance mechanisms to protoporphyrin-mediated photodynamic therapy in human cutaneous squamous cell carcinoma cell lines
2022, Photodiagnosis and Photodynamic TherapyCitation Excerpt :All three abovementioned key elements have been investigated to some extent before, however, scarcely so in cell lines of NMSC, and frequently the published observations have not been consequently linked to resistance [20–22]. Tumor tissues often show increased PpIX accumulation compared to their healthy counterparts, e.g., liver [23], gastrointestinal [24], bladder [25] or brain tissue [26], and also in skin: In a direct comparison between a squamous cell carcinoma cell line and healthy, virus-immortalized keratinocytes, neoplastic cells produced more PpIX from the precursor 5-ALA than healthy cells [20]. Likely candidates for 5-ALA uptake are genes of the solute carrier transporter (SLC) family, especially the SLC6, SLC15 and SLC36 subfamilies due to molecular structure similarity of 5-ALA to endogenous substrates of these transporters [27].
Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT
2022, Photodiagnosis and Photodynamic TherapySignificance of in vitro photodynamic cytodiagnosis with 5-aminolevulinic acid in biliary brush cytology for malignant biliary stricture
2022, Photodiagnosis and Photodynamic Therapy
- *
This study was supported by the Bundesministeriumfar Forschung and Technologie (German government) and Friedrich-Baur Stiftung (University of Munich).