Elsevier

The Lancet

Volume 239, Issue 6183, 28 February 1942, Pages 252-259
The Lancet

ORIGINAL ARTICLES
PHYSIOLOGICAL EFFECTS OF BLAST

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    • Autonomic responses to blast overpressure can be elicited by exclusively exposing the ear in rats

      2018, Journal of Otology
      Citation Excerpt :

      We hypothesize that energy from blast overpressure could enter the unprotected ear canal, traverse these soft tissues into the cranial vault, and directly impact the brain. In this study, we tested the hypothesis that the ear provides a vulnerable locus for blast energy to impact the brain while causing acute autonomic responses typically observed in whole-body paradigms of blast exposure (Guy et al., 1998; Krohn et al., 1942; Sawdon et al., 2002). To do so, we developed a blast generator that delivers precisely controlled blast overpressure waves targeted to a small area of tissue, with minimal impact on the surrounding tissues (Fig. 1A).

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    1

    Beit Memorial Research Fellow.

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