EXPERIMENTS ON THE BLOOD IN CHOLERA.
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William Brooke O'Shaughnessy, an Irishman who introduced anaesthesia to India and brought eastern medicine to Britain
2023, British Journal of AnaesthesiaBridge over Troubled Water: Fluid in the Intensive Care Unit
2019, Physician Assistant ClinicsCitation Excerpt :The first described use of saline fluid was by Thomas Latta in 1832. During London’s cholera epidemic, he treated patients with a type of saline fluid that would “restore blood to its natural specific gravity” and “restore its deficient saline matters.”1,2 He reported his results in a letter to the London Board of Health and the Lancet.
The history of 0.9% saline
2008, Clinical NutritionCitation Excerpt :Having trialled his proposal on a dog, with no ill effects, he recommended his method be used “in the fearful cases in which venesection is found impossible”. O'Shaughnessy then travelled to Sunderland to study the disease17 and submitted a preliminary report to the Lancet detailing his experiments on the blood in cholera.18 His report to the Central Board of Health of London was also later reviewed by the Lancet.19
William O'Shaughnessy, Thomas Latta and the origins of intravenous saline
2002, ResuscitationFrom alchemy to fluid, electrolyte, and acid-base disorders
2014, New England Journal of Medicine