CommentClinical update: sporadic primary hyperparathyroidism
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Cited by (48)
Comparative prospective study on the presentation of normocalcemic primary hyperparathyroidism. Is it more aggressive than the hypercalcemic form?
2020, American Journal of SurgeryCitation Excerpt :Primary hyperparathyroidism (PHPT) is one of the most common endocrinological disorders and is characterised by excessive and unregulated secretion of the parathyroid hormone (PTH).1,2
Neurologic disorders of mineral metabolism and parathyroid disease
2014, Handbook of Clinical NeurologyCitation Excerpt :Inappropriate secretion of PTH in the absence of external stimuli results in an unwarranted increase in bone resorption, renal calcium reabsorption, renal phosphate excretion, and intestinal calcium absorption, leading to hypercalcemia and hypophosphatemia (DeLellis et al., 2008). Elevated PTH also promotes further formation of 1,25-D, which increases intestinal calcium absorption and bone resorption (Sitges-Serra and Bergenfelz, 2007). Primary hyperparathyroidism is due to a single parathyroid adenoma in 75–85% of cases, to parathyroid hyperplasia in about 15% of cases, and rarely to parathyroid carcinoma in less than 1% of cases (Fraser, 2009).
Severe metabolic bone disease in pregnancy mimicking malignancy
2014, CMAJ. Canadian Medical Association JournalCitation Excerpt :Multiple factors likely contributed to this delay in diagnosis. Primary hyperparathyroidism is most commonly diagnosed because of symptoms of hypercalcemia or when asymptomatic hypercalcemia is discovered on routine blood chemistry.11 However, in younger patients, less common presentations may contribute to delays in diagnosis.
Incremental value and clinical impact of neck sonography for primary hyperparathyroidism: A risk-adjusted analysis
2013, Canadian Journal of SurgeryRobotic parathyroidectomy is a feasible technique for primary hyperparathyroidism
2024, Langenbeck's Archives of Surgery