ORIGINAL ARTICLESVITAMIN-D DEFICIENCY AND PRIMARY HYPERPARATHYROIDISM
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Vitamin D and Primary Hyperparathyroidism
2015, The Parathyroids: Basic and Clinical Concepts: Third EditionPrimary hyperparathyroidism
2013, Revue de Medecine InterneSocial deprivation and primary hyperparathyroidism
2010, Endocrine PracticeCitation Excerpt :Both vitamin D deficiency and polymorphism in the vitamin D receptor have been associated with PHPT (24, 25). Another suggestion is that suboptimal vitamin D nutrition stimulates growth of parathyroid adenomas by a mechanism unrelated to hypocalcemia or 1, 25-dihydroxyvitamin D deficiency and reduces the calcemic response to PTH; hence, a higher PTH level and an increased number of parathyroid cells are needed to raise the patient’s serum calcium to the increased level that is characteristic of the disease (26). Furthermore, in many Western countries, several of the characteristics of PHPT have improved temporally with the improvement in vitamin D nutrition.
Asymptomatic primary hyperparathyroidism: A medical perspective
2004, Surgical Clinics of North AmericaPrimary hyperparathyroidism: When to observe and when to operate
2000, Endocrinology and Metabolism Clinics of North AmericaCitation Excerpt :On the basis of their remarkable improvement in bone mineral density at the lumbar spine, the author recommends that such patients be considered for parathyroidectomy.46 In countries where vitamin D deficiency is common among patients with primary hyperparathyroidism, the hyperparathyroid disease is worse.31,56 Many years ago, Lumb and Stanbury31 postulated that vitamin D deficiency in patients with primary hyperparathyroidism gave rise to more symptomatic disease.
Diagnosis of asymptomatic primary hyperparathyroidism: Proceedings of the third international workshop
2009, Journal of Clinical Endocrinology and Metabolism