Solitary fibrous tumor of the orbit: Is it rare? Report of a case series and review of the literature☆
Section snippets
Patients and methods
Four patients sought treatment for a unilateral orbital mass and were treated successfully with surgical excision by three of the authors (CDC, RCK, and FPB); one case was a recurrent tumor occurring after incomplete initial excision. Before surgery, a benign lesion was suspected in all four cases, but orbital solitary fibrous tumor was not included in the preoperative differential diagnosis. The final diagnosis relied on the distinctive histologic pattern and immunohistochemical staining.
Patient 1
A 27-year-old white man had a 1-year history of an expanding mass in the medial aspect of the right lower eyelid (Fig 1). On examination, pupils, Extraocular muscle (EOM) examination results, and visual acuity were normal. An anterior orbital mass was palpable through the medial one third of the right lower eyelid and was oval, well delineated, mobile, and separate from the surrounding orbital tissue. Retropulsion and Hertel exophthalmometry results were unremarkable, but the globe was
Discussion
Solitary fibrous tumor is a spindle-shaped cell neoplasm, that has been described on the mesothelial surfaces of pleura and mediastinum. Originally, this entity was thought to be of mesothelial origin and was referred to as a “localized mesothelioma.” More recently, this tumor has been described in many extraserosal sites, such as lung, liver, paranasal sinuses, and orbit, where no mesothelial lining exists, thus supporting a fibroblastic origin. Solitary fibrous tumor should be differentiated
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Manuscript No. 210996.