Color Doppler Imaging of the Ophthalmic Artery Blood Flow Spectra of Patients Who Have Had a Transient Ischemic Attack: Correlations with Generalized Iris Transluminance and Pseudoexfoliation Syndrome
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Retinal nerve fiber layer and ophthalmic artery blood flow parameters in pseudoexfoliation syndrome and pseudoexfoliative glaucoma
2023, Journal Francais d'OphtalmologieAssociation of pseudoexfoliation syndrome with cardiovascular and cerebrovascular disease: a systematic review and meta-analysis
2018, Canadian Journal of OphthalmologyCitation Excerpt :Ultimately, PEX was found to be significantly associated with CVA in every sensitivity analysis performed. Of note, 2 studies by Repo et al.44,45 were excluded from analysis despite reporting prevalence of CVA among PEX and non-PEX groups because they reported the number of eyes with PEX instead of the number of individuals with PEX. Summary ORs were generated to include these articles, both with generous (i.e., 1 eye to 1 individual) and conservative (i.e., 2 eyes to 1 individual) numbers; results were statistically significant, although ORs were inflated and heterogeneity was induced.
Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology
2017, Experimental Eye ResearchCitation Excerpt :XFS is a systemic disorder that is increasingly being associated with non-ocular diseases. Epidemiological studies show that XFS increases risk for coronary artery disease (Andrikopoulos et al., 2009; Citirik et al., 2007; Demir et al., 2011; Mitchell et al., 1997; Wang et al., 2014), hypertension (Katsi et al., 2013), cerebrovascular disease (Repo et al., 1995; Ritland et al., 2004; Yuksel et al., 2006), abdominal aortic aneurysm (Djordjevic-Jocic et al., 2012; Schumacher et al., 2001), peripheral vascular disease (Praveen et al., 2011), renal artery stenosis (Gonen et al., 2013), erectile dysfunction (Gokce and Gokce, 2015), Alzheimer's-like dementia (Linner et al., 2001; Cumurcu et al., 2013), sensorineural hearing loss (Cahill et al., 2002; Yazdani et al., 2008), and, most recently, pelvic organ prolapse (Wirostko et al., 2016). The exact mechanism underlying the development of vascular complications in XFS remains poorly understood, although abnormal elastic fiber synthesis in vessel walls, elevated serum antiphospholipid antibody levels, increased oxidative stress, endothelial dysfunction and hyperhomocysteinemia are all hypothesized to play contributory roles (Ritch, 2014; Akarsu and Unal, 2005; Visontai et al., 2006; Naji et al., 2008; Altintas et al., 2012; Hollo, 2014; Tosun et al., 2012).
Pseudoexfoliation Glaucoma: Clinical Presentation and Therapeutic Options
2023, Turkish Journal of Ophthalmology