Impact of intraocular pressure regulation on visual fields in open-angle glaucoma1☆,
Section snippets
Materials and methods
The 76 patients included in this study had all completed participation in a Swedish prospective, randomized study in which primary treatment with argon laser trabeculoplasty was compared with pilocarpine medication.22, 23, 24, 25 Of the 82 patients in this original study, 6 patients were excluded because of fewer than 8 reliable visual field examinations. One patient died 10 months after inclusion, and two patients wanted to discontinue the study. The remaining three patients were excluded
All eyes
The basic characteristics of the whole group of patients and the subgroups with capsular and simple glaucoma with respect to the IOP variables are given in Table 1. Correlations between the IOP variables in these groups are listed in Table 2. As seen in this table and confirmed by the principal component analysis, the correlation between IOP at start and IOP change was high, and the correlations between the four remaining IOP parameters (random, mean, range, and peak) were also fairly high.
Discussion
The primary objective of this clinical study was to compare primary argon laser trabeculoplasty with primary medical treatment (pilocarpine). Primary argon laser trabeculoplasty proved to be advantageous in terms of lowering IOP and preventing visual field loss and damage to the optic nerve head.22, 23, 24 These findings are similar to those in the Glaucoma Laser Trial in the United States.14, 30
This article deals with a secondary purpose of the study, namely to investigate the association
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Supported in part by the Foundation of Crown Princess Margareta of Sweden.
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The authors have no proprietary interest in any of the materials used in this study.