The dopaminergic mesencephalic projections to the hippocampal formation in the rat

doi:10.1016/S0278-5846(96)00157-1

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volume 21, Issue 1, January 1997, Pages 1-22

https://doi.org/10.1016/S0278-5846(96)00157-1 Get rights and content

Abstract

1.
1. The dopaminergic mesencephalic neurons projecting to the hippocampal formation are distributed in three cell groups: A8 region in the retrorubral field, A9 region in the substantia nigra and A10 region in the ventral tegmental area.
2.
2. Anterograde and retrograde tract-tracing techniques combined with immunohistochemical procedures indicate a topographical organization of mesencephalic dopaminergic projections towards the hippocampal formation.
3.
3. Electrophysiological evidence suggest that dopaminergic mesencephalic neurons could have a regulatory role in suppressing hippocampal excitability.
4.
4. The functional significance of the mesohippocampal dopaminergic system is largely unknown, although it was suggested that this projection could have a role in methamphetamine-produced hypermotility and in modulation of memory processes.

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Critical review and theoretical articleThe dopaminergic mesencephalic projections to the hippocampal formation in the rat

Abstract

Brain Res. Rev.

Neurosci. Lett.

Life Sci.

Exp. Neurol.

Prog. Neurobiol.

Brain Res. Bull.

Neuroscience

Brain Res.

Brain Res.

Brain Res.

Behav. Biol.

Life Sci.

Neuroscience

Pharmacol. Biochem. Behav.

Eur. J. Pharmacol.

Neuroscience

Behav. Brain Res.

Neuropharmacology

Brain Res.

Neuroscience

Neurosci. Lett.

Brain Res.

Brain Res.

Brain Res.

Neuroscience

Brain Res. Bull.

Brain Res.

Brain Res.

Brain Res.

Neuroscience

Neuroscience

Organization of the ascending projections from the ventral tegmental area: A multiple fluorescent retrograde tracer study in the rat

J. Comp. Neurol.

A quantitative study on the nigro-striatal dopamine neuron system in the rat

Acta Physiol. Scand.

Distribution and morphological characteristics of dopamine-immunoreactive neurons in the midbrain of the squirrel monkey (Saimiri Sciureus)

J. Comp. Neurol.

A possible enabling and enhancing function for cathecolamines in neuronal plasticity

Histamine synthesizing afferents to the hippocampal region

J. Neurochem.

Dopamine action on hippocampal pyramidal cells

J. Neurosci.

Dopamine modulates a Ca2+-activated potassium conductance in mammalian hippocampal pyramidal cells

Nature

Mesohippocampal dopamine system: Characterization, functional and clinical implications

Micro-electrophoretic studies of neurones in the cat hippocampus

J. Physiol.

In the general discussion. 1. Monoaminergic inputs to the hippocampus

The mesotelencephalic dopamine neuron system: A review of its anatomy

A synaptic model of memory- Long-Term Potentiation in the hippocampus

Nature

Midbrain dopaminergic systems:Neurophysiology and electrophysiological pharmacology

The occurrence, distribution and physiological role of catecholamines in the nervous system

Pharmacol. Rev.

Cellular localization of brain monoamines

Acta Physiol. Scand.

Effects of the stimulation of the retrorubral field on the excitability of the rat hippocampus

Neurosci. Lett.

Dopamine and norepinephrine in noradrenergic axons: A study in vivo of precursor product relationship by mass fragmentary and radiochemistry

Pharmacol. Rev.

Evidence for the existence of monoamine-containing neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brainstem neurons

Acta Physiol. Scand.

Critical review and theoretical article
The dopaminergic mesencephalic projections to the hippocampal formation in the rat

Dopamine modulates a Ca²⁺-activated potassium conductance in mammalian hippocampal pyramidal cells