Research LettersAmbroxol-induced systemic contact dermatitis confirmed by positive patch test
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Cited by (7)
Pilot study using ambroxol as a pharmacological chaperone in type 1 Gaucher disease
2013, Blood Cells, Molecules, and DiseasesCitation Excerpt :The ambroxol dose of 1 g/kg was administered to these rats to achieve plasma levels comparable to those in clinical use (for IRDS). Among the isolated reports of single adverse events reported with ambroxol in the non-English language literature in the past decade [20–22], but in the rat model, was that at doses of 30 mg and 60 mg/kg/24 h there was induction of xanthine and calcium oxalate stones [23]. In addition to mucus regulation and local anesthetic effects, ambroxol apparently has a wide range of pharmacological anti-inflammatory properties [24], inflammation often being considered as one of the underlying pathogenic effects of the abnormal substrate accumulation in Gaucher disease [6,25] as well as in other lysosomal diseases.
MONOGRAPHS IN CONTACT ALLERGY, VOLUME 4: SYSTEMIC DRUGS
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2016, British Journal of DermatologyEfficacy of Ambroxol lozenges for pharyngitis: A meta-analysis
2014, BMC Family Practice
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