Cloning of mouse BMAL2 and its daily expression profile in the suprachiasmatic nucleus: a remarkable acceleration of Bmal2 sequence divergence after Bmal gene duplication
Section snippets
Acknowledgements
We thank Dr Daisuke Kojima for help in constructing phylogenetic tree, Dr Kimiko Shimizu for technical advice and Takaoki Kasahara and Tsuyoshi Hirota for technical assistance. This work was supported in part by Grants-in-aid from the Japanese Ministry of Education, Culture, Sports, Science and Technology.
References (20)
- et al.
A serum shock induces circadian gene expression in mammalian tissue culture cells
Cell
(1998) - et al.
cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS protein (BMAL1) and identification of alternatively spliced variants with alternative translation initiation site usage
Biochem. Biophys. Res. Commun.
(1997) - et al.
cDNA cloning of a novel bHLH-PAS transcription factor superfamily gene, BMAL2: its mRNA expression, subcellular distribution, and chromosomal localization
Biochem. Biophys. Res. Commun.
(2000) - et al.
A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock
Cell
(1999) - et al.
CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression
J. Biol. Chem.
(2000) - et al.
Transcriptionally active heterodimer formation of an Arnt-like protein, Arnt3, with HIF-1α, HLF, and Clock
Biochem. Biophys. Res. Commun.
(1998) - et al.
MOLPHY: programs for molecular phylogenetics based on maximum likelihood, Version 2.3
(1996) - et al.
Asynchronous oscillations of two zebrafish CLOCK partners reveal differential clock control and function
Proc. Natl. Acad. Sci. USA
(2000) PHYLIP, Version 3.572
(1996)- et al.
Role of the CLOCK protein in the mammalian circadian mechanism
Science
(1998)
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These authors contributed equally to this work.