Panniculitis

Erythema nodosum

Erythema nodosum is the most common of the panniculitides. It is best considered a reactive process to a variety of possible inciting causes and is manifested as an inflammatory reaction in the subcutaneous tissue. The most common identifiable cause of erythema nodosum is a beta-streptococcal upper respiratory tract infection, although other infections, drugs, inflammatory bowel disease, pregnancy, autoimmune diseases, and malignant diseases have also been recognized [5]. The condition may also

Superficial migratory thrombophlebitis

Superficial thrombophlebitis is seen most often in patients with venous insufficiency; however, a hypercoagulable state should be excluded [28], [29]. Behçet syndrome may present with superficial thrombophlebitis and organ thrombosis [30]. Historical literature describes superficial thrombophlebitis as a paraneoplastic syndrome (Trousseau's sign) associated with pancreatic, stomach, lung, prostate, colon, and bladder carcinoma [31]. The disease is characterized by multiple tender erythematous

Idiopathic lobular panniculitis (Weber-Christian disease)

Also called acute febrile nonsuppurative nodular panniculitis, this condition is probably not a single disease entity but represents various entities presenting as a lobular panniculitis that cannot be more specifically classified. As originally described, Weber-Christian disease was said to be caused by three broad groups of etiologic factors: physical and chemical agents, infectious agents, and immunologic factors. Many of these conditions should be given more specific diagnoses related to

Nodular vasculitis

Panniculitis caused by nodular vasculitis is thought to represent a hypersensitivity reaction to an underlying antigenic stimulus. Bacterial infections, including streptococcal infection, have been implicated, as have drugs and, occasionally, mycobacterial infections. In the latter case, the histology characteristically includes tuberculoid granulomas, and the condition has been referred to as erythema induratum of Bazin [67].

The disease can occur at any age although middle age women are most