Elsevier

Journal of Voice

Volume 14, Issue 2, June 2000, Pages 247-254
Journal of Voice

The proximal probe in esophageal pH monitoring: Development of a normative database*

https://doi.org/10.1016/S0892-1997(00)80033-8Get rights and content

Summary

Healthy volunteers without symptoms of either gastroesophageal reflux or laryngopharyngeal reflux and without abnormalities on laryngologic examination were recruited for esophageal pH monitoring. Thirty subjects underwent ambulatory 24-hour double-channel pH probe monitoring to establish normative data for the upper probe, which was positioned just above the upper esophageal sphincter. Data were analyzed excluding meal periods plus 2 minutes of postprandial time. The mean, standard deviation, median, and 95th percentile were calculated for various reflux parameters for the following intervals: total study duration, upright time, supine time, and postprandial time. Normal subjects display physiologic reflux above the upper esophageal sphincter (median one event, 95th percentile 6.9 events), and 80.4% of these events occur in the upright position. The reflux area index (RAI) appears to be the most useful parameter to measure laryngopharyngeal reflux severity.

References (13)

  • MetzDC et al.

    Pilot study of the oral omeprazole test for reflux laryngitis

    Otolaryngol Head Neck Surg

    (1997)
  • JacobP et al.

    Proximal esophageal pH-metry in patients with ‘reflux laryngitis’

    Gastroenterology

    (1991)
  • KoufmanJA

    The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury

    Laryngoscope

    (1991)
  • ShawGY et al.

    Laryngeal manifestations of gastroesophageal reflux before and after treatment with omeprazole

    South Med J.

    (1997)
  • HansonDG et al.

    Outcomes of antireflux therapy for the treatment of chronic laryngitis

    Ann Otol Rhinol Laryngol

    (1995)
  • WardPH et al.

    Reflux as an etiological factor in carcinoma of the laryngopharynx

    Laryngoscope

    (1988)
There are more references available in the full text version of this article.

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*

This paper was presented for the Voice Foundation's 27th Annual Symposium: Care of the Professional Voice, Philadelphia, Pennsylvania, June 1998

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