Osteosarcoma of the craniofacial bones: A Clinico-Pathological study

https://doi.org/10.1016/S1010-5182(05)80614-6Get rights and content

Summary

Thirty-four cases of osteosarcoma involving the craniofacial bones over a period of 19 years were reviewed. They formed 6.2% of osteosarcomas occurring in the skeleton during the same period at the Tata Memorial Hospital. Mean age of occurrence was 30.9% years, with a range of 7 to 61 years. Male preponderance was noted in maxillary tumours (M:F=2.6:1), while the mandibular tumours occurred with equal frequency in both sexes. The mandible was the bone of origin in 56%, maxilla in 32% and other craniofacial bones in 12% of patients. Histological sub-type did not affect the prognosis. Radical surgery with resection of adequate disease-free margins is the most effective mode of treatment. Morbidity and mortality is due to extensive local recurrence of disease, particularly with maxillary tumours. Metastasis to other organs occurs rarely. No statistically significant difference in survival was observed between tumours of the mandible and maxilla, or between patients above and below 20 years of age.

References (22)

  • ClarkJ.L. et al.

    Osteosarcoma of the Jaws

    Cancer

    (1983)
  • Cited by (78)

    • An Indian perspective on gnathic osteosarcoma: A comprehensive literature review of the last three decades

      2014, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
    • Incidence and grading of cranio-facial osteosarcomas

      2014, International Journal of Oral and Maxillofacial Surgery
      Citation Excerpt :

      A summary is given in Table 2. Only six reports were based on primary tumours alone; a comparison of these data with the data from all reports found in the literature and our data is given in Table 3.7,10,14,16,18,29 Osteosarcomas are mostly noted in the long bones and are presumed to have the highest incidence in the second decade of life.

    • A rapidly enlarging mandibular swelling

      2013, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
    View all citing articles on Scopus
    View full text