Editorial: Time is brain!
References (24)
The use of anticoagulants in cerebral thrombosis
Neurology
(1958)Anticoagulant therapy in cerebral thrombosis and cerebral embolism. A national cooperative study, interim report
Neurology
(1961)Anticoagulant treatment in progressing stroke
Br Med J
(1961)- et al.
Anticoagulant therapy in cerebral infarction
Neurology
(1962) - et al.
A double-blind trial of naloxone in the treatment of acute stroke
Stroke
(1984) The effect of nimodipine on the clinical course of patients with acute ischemic stroke
Acta Neurol Scand
(1984)- et al.
A controlled trial of nimodipine in acute ischemic stroke
N Engl J Med
(1988) - et al.
Failure of naloxone to reverse vascular neurologic deficits
Neurology
(1983)
Naloxone administration to patients with acute stroke
Stroke
A dose-escalation study of large doses of naloxone for treatment of patients with acute cerebral ischemia
Stroke
Cited by (62)
Thrombus composition and thrombolysis resistance in stroke
2023, Research and Practice in Thrombosis and HaemostasisLanguage is brain: Improving neurologic health equity for linguistically diverse populations
2022, Journal of Clinical NeuroscienceCitation Excerpt :All languages share a common neural substrate, the (typically) left perisylvian network. Hence, drawing on the widely known expression “time is brain,” which has been used as a call to action regarding the urgency of stroke care [1,2], we argue that “language is brain,” as well. Despite United States (US) federal regulations mandating non-discrimination on the basis of language [3], communicating with patients who have non-English language preference (NELP) remains an unresolved health equity challenge [4].
Posterior Circulation Stroke: Coma (More Than Time) is Brain
2022, Journal of Stroke and Cerebrovascular DiseasesCitation Excerpt :Indeed, the authors believe that often a low GCS makes endovascular treatment seem more necessary, and our results may very well suggest the contrary – that the presence of coma may weigh against treatment and that these cases warrant strict decision making. The basis for the rationale of “time is brain”22 is the existence of collateral circulation and how distant hemispheric vessels (often leptomeningeal) can compensate a hypoperfused territory.23 On the contrary, the Pcom, regarded as a key element of collateral supply in the posterior circulation,13,24 are relatively close to the basilar artery, and provide means of irrigation to vascular territories that are largely determined by perforating branches.
Impact of the SARS-COV-2 Pandemic on the Endovascular Treatment of Acute Stroke – an Italian Single-Center Experience
2021, Journal of Stroke and Cerebrovascular DiseasesCitation Excerpt :Under the banner of “time is brain”,1 the race towards achieving the fastest treatment in acute stroke is ongoing.
Stroke priorities during COVID-19 outbreak: acting both fast and safe
2020, Journal of Stroke and Cerebrovascular DiseasesCitation Excerpt :Current acute stroke management guidelines recommend designing and implementing public education programs focused on stroke systems, referring acute stroke patients to emergency care and evaluating risk factors for patients presenting with TIA.14 Since AIS is a time-dependent disease and the treatment effectiveness is mainly related to timely access to the therapy,25,26 current guidelines state that emergency therapy should be administrated quickly avoiding unnecessary and potentially time-consuming procedures.14,27 Before COVID-19 outbreak, stroke guidelines have been universally accepted by clinicians involved in acute stroke.14