Original articleGestational diabetes mellitus and the risk of metabolic syndrome: a population-based study in Lausanne, Switzerland
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2020, Mayo Clinic ProceedingsCitation Excerpt :When assessing women for cardiovascular risk, it is important to be aware of such risk factors that might have contributed to premature aging of the vasculature. Gestational diabetes mellitus occurs in 2% to 10% of pregnancies and confers a 4- to 7-fold higher risk of future type II diabetes and the development of the metabolic syndrome in midlife.64,65 These patients also have a higher risk of CAD, myocardial infarction, and stroke.66
Increased risk of non-alcoholic fatty liver disease in women with gestational diabetes mellitus: A population-based cohort study, systematic review and meta-analysis
2019, Journal of Diabetes and its ComplicationsCitation Excerpt :There are several potential mechanisms linking GDM to NAFLD development. GDM results from the inability to adapt to complex metabolic needs during gestation and leads to an increased risk of metabolic syndrome36 and type 2 diabetes development in later life.37,38 GDM has been linked to subsequent lipid abnormalities, hyperinsulinaemia/insulin resistance and increased systematic inflammation especially in overweight or obese women.39–41
Impact of probiotics in women with gestational diabetes mellitus on metabolic health: A randomized controlled trial
2015, American Journal of Obstetrics and GynecologyCitation Excerpt :There are discrepancies in the literature regarding differences in maternal lipid levels in GDM vs healthy pregnancy24-27 and what constitutes “optimal” lipid levels in pregnancy remains unclear. Despite this, dyslipidemia has been detected among pregnant women prior to GDM diagnosis,24,28 which may indicate a risk factor for the development of impaired glycemia in pregnancy and metabolic syndrome postpartum. A review of the cholesterol-lowering effects of probiotics and prebiotics reported conflicting results among various studies in nonpregnant human beings,29 which may be attributed to variations in probiotic strains, clinical characteristics of participants, study design, and sample sizes.
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