ArticleMaternal age-related differential global expression profiles observed in human oocytes
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Dr Steuerwald began her career in mathematics and computer science, but later went on to pursue advanced studies in reproductive biology. Dr Steuerwald received a PhD from Florida International University in Miami, USA in 1999. She completed her dissertation research in the laboratory of Drs Jacques Cohen and Santiago Munné, with whom she collaborated to conduct quantitative expression analysis in single oocytes with particular emphasis on cell cycle regulation and checkpoint gene expression
References (55)
First-meiotic-division nondisjunction in human oocytes
American Journal of Human Genetics
(1997)- et al.
Mitochondrial DNA point mutation in human oocytes is associated with maternal age
Reproductive BioMedicine Online
(2000) - et al.
The syntaxin family of vesicular transport receptors
Cell
(1993) - et al.
Expression profiles of individual human oocytes using microarray technology
Reproductive BioMedicine Online
(2004) - et al.
Cytoplasmic remodelling and the acquisition of developmental competence in pig oocytes
Animal Reproduction Science
(2007) - et al.
Demonstration of a mechanism of aneuploidy in human oocytes using Multifluor fluorescence in situ hybridization
Fertility and Sterility
(2001) - et al.
The Ran GTPase mediates chromatin signaling to control cortical polarity during polar body extrusion in mouse oocytes
Developmental Cell
(2007) - et al.
Spindles, mitochondria and redox potential in ageing oocytes
Reproductive BioMedicine Online
(2004) - et al.
The SUV3 gene from Saccharomyces douglasi is a functional equivalent of its Saccharomyces cerevisiae orthologue and is essential for respiratory growth
FEMS Yeast Research
(2004) - et al.
Aging and the ubiquitinome: Traditional and non-traditional functions of ubiquitin in aging cells and tissues
Experimental Geontology
(2006)
Mitochondrial deoxyribonucleic acid deletions in oocytes and reproductive aging in women
Fertility and Sterility
Paternal and maternal factors in preimplantation embryogenesis: interaction with the biochemical environment
Reproductive Biomedicine Online
Chromosome abnormalities and their relationship to morphology and development of human embryos
Reproductive BioMedicine Online
Preimplantation genetic diagnosis and human implantation – a review
Placenta
Age-related decline in female fertility is not due to diminished capacity of the uterus to sustain embryo implantation
Fertility and Sterility
Poor oocyte quality rather than implantation failure as a cause of age-related decline in female fertility
Lancet
Golgi dynamics during meiosis are distinct from mitosis and are coupled to endoplasmic reticulum dynamics until fertilization
Developmental Biology
Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria
Cell
Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells
Stem Cells
Influence of maternal age on meiotic spindle assembly in oocytes from naturally cycling women
Human Reproduction
Molecular analysis of maturation processes by protein and phosphoprotein profiling during in-vitro maturation of bovine oocytes: a proteomic approach
Cloning Stem Cells
Structure and function of SNARE and SNARE-interacting proteins
Quarterly Reviews of Biophysics
The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain
Journal of Biological Chemistry
Spatial coordination of spindle assembly by chromosome-mediated signaling gradients
Science
Influence of follicular fluid meiosis-activating sterol on aneuploidy rate and precocious chromatid segregation in aged mouse oocytes
Human Reproduction
Sequential FISH analysis of oocytes and polar bodies reveals aneuploidy mechanisms
Prenatal Diagnosis
Association between nondisjunction and maternal age in meiosis-II human oocytes
American Journal of Human Genetics
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Dr Steuerwald began her career in mathematics and computer science, but later went on to pursue advanced studies in reproductive biology. Dr Steuerwald received a PhD from Florida International University in Miami, USA in 1999. She completed her dissertation research in the laboratory of Drs Jacques Cohen and Santiago Munné, with whom she collaborated to conduct quantitative expression analysis in single oocytes with particular emphasis on cell cycle regulation and checkpoint gene expression during meiosis. Currently Dr Steuerwald is involved in the development of clinically relevant microarray methods and is interested in research involving the application of bioinformatics.