Original investigationReal-Time Sonoelastography of the Cervix: Tissue Elasticity of the Normal and Abnormal Cervix
Section snippets
Materials and methods
The patients enrolled in this study were inpatients of a university women’s hospital who underwent a gynecologic examination with transvaginal US between May and July 2005. The routine vaginal US examination was supplemented by additional sonoelastography. The examiner performing sonoelastography (A.T.) was blinded to the patients’ clinical and histologic diagnoses at the time of examination. Of the 115 patients examined during this period, 90 women had normal cervical findings (normal group).
Results
Two of the 115 patients examined were excluded from analysis. Twenty-four of the 113 patients included had histologically proven cervical lesions (21.2%). The women had a mean age of 45 years with a range of 17−79 years. In the normal group, 49 women were premenopausal and 40 postmenopausal. Of the 24 patients with cervical lesions, 17 were premenopausal and 7 postmenopausal.
Discussion
Cervical cancer is the second most common malignancy in women worldwide (25). Screening programs in western countries have reduced the incidence of cervical cancer while more precancerous conditions are diagnosed (20). Although vaccination against human papilloma virus, one of the main causes of cervical cancer, may further reduce the incidence in the future, early diagnosis is still the most important factor for survival (26, 27).
Imaging has only a minor role in the diagnosis of cervical
References (31)
- et al.
A new elastographic method for estimation and imaging of lateral displacements, lateral strains, corrected axial strains and Poisson’s ratios in tissues
Ultrasound Med Biol
(1998) - et al.
Elastography imaging of small animal oncology models: A feasibility study
Ultrasound Med Biol
(2003) - et al.
A quantitative comparison of modulus images obtained using nanoindentation with strain elastograms
Ultrasound Med Biol
(2004) - et al.
Categorizing breast mammographic density: Intra- and interobserver reproducibility of BI-RADS density categories
Breast
(2005) - et al.
Interleukin-8 synthesis and the onset of labor
Obstet Gynecol
(1995) - et al.
Cancer burden in the year 2000The global picture
Eur J Cancer
(2001) - et al.
Real-time sonoelastography performed in addition to B-mode ultrasound and mammography: Improved differentiation of breast lesions?
Acad Radiol
(2006) - et al.
Elastic moduli of breast and prostate tissues under compression
Ultrason Imaging
(1998) - et al.
Elastographic imaging
Ultrasound Med Biol
(2000) - et al.
Evaluation of renal parenchymal disease in a rat model with magnetic resonance elastography
Magn Reson Med
(2004)
Elastographie: Quantitative Bildgebung der elastischen Gewebeeigenschaften
Fortschr Röntgenstr
MR-Elastographie der Prostata: Erste In-vivo-Anwendung
Fortschr Röntgenstr
Magnetic resonance elastography of the breast: correlation of signal intensity data with viscoelastic properties
Invest Radiol
Realtime elastographyA new ultrasound procedure for the reconstruction of tissue elasticity
Radiologe
An advanced method of ultrasound–real-time elastography: First results in 108 patients with breast lesions
Ultrasound Obstet Gynecol
Cited by (148)
Evaluation of Pre-malignant Lesions of the Uterine Cervix by Shear Wave Elastography: A New Diagnostic Tool
2021, Ultrasound in Medicine and BiologyAdvancements in the Application of Ultrasound Elastography in the Cervix
2021, Ultrasound in Medicine and BiologyCitation Excerpt :Strain elastography is the most widely used elastic imaging method in cervical diseases. Thomas et al. (2007) found a statistically significant difference in the elastic properties between the normal cervix and cervical cancer but no significant difference between the normal cervix and CIN (n = 113). They used color distribution (red represents soft tissue, blue represents hard tissue and green represents medium tissue hardness) of cervical tissue in the computer-assisted analysis to evaluate the elastic properties.
Temperature Elevation in an Instrumented Phantom Insonated by B-Mode Imaging, Pulse Doppler and Shear Wave Elastography
2020, Ultrasound in Medicine and BiologyTemperature Rise Caused by Shear Wave Elastography, Pulse Doppler and B-Mode in Biological Tissue: An Infrared Thermographic Approach
2020, Ultrasound in Medicine and BiologyCitation Excerpt :The first consensus meeting was held in March 2013 and led to the development of guidelines for basic science in elastography (Shiina et al. 2015) and for the use of this technique for the breast (Barr et al. 2015) and liver (Ferraioli et al. 2015), without distinguishing between the different elastography modes. Elastography has recently been applied to gynecology (Thomas et al. 2007; Ami et al. 2009) and obstetrics (Kiliç et al. 2015; Alan et al. 2016; Quarello et al. 2016). Many published articles already deal with tissues that are accessible to methods necessitating the direct compression of the organ with the ultrasound probe, such as the cervix (Molina et al. 2012; Khalil et al. 2013; Hernandez-Andrade et al. 2014; Fruscalzo et al. 2016; O'Hara et al. 2018).
Ultrasound elastography in neuromuscular and movement disorders
2019, Clinical ImagingThe role of cervical elastography in the differential diagnosis of preinvasive and invasive lesions of the cervix
2024, Archives of Gynecology and Obstetrics