Elsevier

Academic Radiology

Volume 21, Issue 4, April 2014, Pages 431-436
Academic Radiology

Original Investigation
Optimization of Kiloelectron Volt Settings in Cerebral and Cervical Dual-energy CT Angiography Determined with Virtual Monoenergetic Imaging

https://doi.org/10.1016/j.acra.2013.12.006Get rights and content

Rationale and Objectives

Dual-energy computed tomography (DECT) offers various fields of application, especially in angiography using virtual monoenergetic imaging. The aim of this study was to evaluate objective image quality indices of calculated low–kiloelectron volt monoenergetic DECT angiographic cervical and cerebral data sets compared to virtual 120-kV polyenergetic images.

Materials and Methods

Forty-one patients (21 men, mean age 58 ± 14) who underwent DECT angiography of the cervical (n = 7) or cerebral vessels (n = 34) were retrospectively included in this study. Data acquired with the 80 and 140 kVp tube using dual-source CT technology were subsequently used to calculate low-kiloelectron volt monoenergetic image data sets ranging from 120 to 40 keV (at 10-keV intervals per patient). Vessel and soft tissue attenuation and image noise were measured in various regions of interest, and contrast-to-noise ratio (CNR) was subsequently calculated. Differences in image attenuation and CNR were compared between the different monoenergetic data sets and virtual 120-kV polyenergetic images.

Results

For cervical angiography, 60-keV monoenergetic data sets resulted in the greatest improvements in vessel attenuation and CNR compared to virtual 120-kV polyenergetic data sets (+40%, +16%; all P < .01). Also for cerebral vessel assessment, 60-keV monoenergetic data sets provided the greatest improvement in vessel attenuation and CNR (+40%, +9%; all P < .01) compared to virtual 120-kV polyenergetic data sets.

Conclusions

60-keV monoenergetic image data significantly improve vessel attenuation and CNR of cervical and cerebral DECT angiographic studies. Future studies have to evaluate whether the technique can lead to an increased diagnostic accuracy or should be used for dose reduction of iodinated contrast material.

Section snippets

Study Population

This retrospective data analysis was performed in accordance with the Health Insurance Portability and Accountability Act and the Declaration of Helsinki. Institutional review board approval and the need for written informed consent were waived because of the retrospective nature of the study. DECT angiographic studies of the neck and the brain were performed for clinical suspicion of vessel occlusion or dissection. No further selection of the patient collective was conducted.

Image Acquisitions

All acquisitions

Results

A total of 102 arteries in 34 Patients (17 men, 17 women, mean age 57 ± 14, range 21–80 years) were analyzed in cerebral DECT angiographic studies. Twenty-one arteries in seven Patients (four men, three women, mean age 67 ± 12, range 40–75 years) were analyzed in the cervical DECT angiographic studies.

Discussion

The purpose of this study was to investigate possible improvements in image quality of DECT angiography of head and neck vessels by comparing varying monoenergetic or monochromatic energy reconstructions with standard 120-kV PEI images. Our results demonstrate that MEIs at optimal energy levels provide superior vessel attenuation and CNR characteristics compared to 120-kV PEI. So far, there is a lack of data within the available literature, which compares objective image quality of

Conclusion

MEI reconstructions provide improved objective image quality in DECT cerebral and cervical angiography compared to standard 120-kVp polyenergetic reconstructions; the optimal energy level was determined as 60 keV for cervical and cerebral angiography. MEI reconstructions at these levels should be considered for clinical use when DECT angiography of the cervical or cranial vessels is performed.

References (20)

There are more references available in the full text version of this article.

Cited by (0)

View full text