Original articleTransient Corneal Thinning in Eyes Undergoing Corneal Cross-Linking
Section snippets
Population
Thirty eyes from 30 consecutive patients (9 female, 21 male) were enrolled into the Cornea Service at the Helsinki University Eye Hospital between January 23 and July 6, 2009. Twenty-four of the eyes had progressive keratoconus, 3 eyes had progressive keratectasia after a LASIK operation, 2 eyes presented with pellucid marginal degeneration, and 1 eye had bullous keratopathy after a cataract operation. All of the patients underwent preoperative and postoperative uncorrected visual acuity (UCVA)
Results
The first 30 patients (9 female, 21 male) who were treated with CXL in the Cornea Service at the Helsinki University Eye Hospital were included in this study. The mean patient age was 38 ± 12 years. The objective of this study was to assess the safety and usefulness of CXL for the treatment of corneal ectasia. Because the most severe threat to corneal fitness posed by CXL treatment is endothelial damage attributable to excessive corneal thinning, we assessed corneal thickness preoperatively,
Discussion
The purpose of this study was to examine corneal thickness behavior during CXL. Essentially, we found that the corneal thickness in each examined patient was significantly reduced during CXL and in some patients it was reduced to a level where the health of the cornea was jeopardized. Corneal hydration was required in 80% of the patients, which forced corneal thickness monitoring during CXL. Corneal thinning during CXL has been previously reported by Kymionis and associates.12 These authors
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