Original articleAccuracy of the Heidelberg Spectralis in the Alignment Between Near-Infrared Image and Tomographic Scan in a Model Eye: A Multicenter Study
Section snippets
Methods
Six ophthalmologic sites were involved in this multicenter study beginning in March of 2012. Sites included were: (1) Jacobs Retina Center and (2) Hamilton Glaucoma Center at the Shiley Eye Center, University of California San Diego, La Jolla, California, USA; (3) Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico and (4) Luigi Sacco Hospital, University of Milan, Milan, Italy; (5) Azienda Ospedaliera Sant’Anna, Como, Italy; and (6) Department of Ophthalmology,
Results
A summary of all results of the 12-week study is presented in the Table. After the calibration procedure at baseline, the mean horizontal error among the 6 sites was 0.54 ± 0.31 pixels, equivalent to 3.10 ± 1.80 μm; the mean vertical error was 0.69 ± 0.12 pixels, equivalent to 3.93 ± 0.68 μm. During the 12-week study, the mean horizontal error among the 6 sites was 2.43 ± 1.20 pixels, equivalent to 13.90 ± 6.89 μm; the mean vertical error was 2.46 ± 1.14 pixels, equivalent to 14.08 ± 6.55 μm.
Discussion
The present study showed that, overall, the alignment between simultaneous NIR images and OCT scans of the Heidelberg Spectralis is excellent. The mean error in the alignment was 13.90 μm (horizontal) and 14.08 μm (vertical), and the mean maximum error was 15.35 μm. Interestingly, the maximum error increased significantly at week 1 compared to baseline (P = .01), then varied randomly without significant changes during the 12-week follow-up period. During the first day after calibration, the
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