Original articleImpact of Donor Age on Descemet Membrane Endothelial Keratoplasty Outcome: Evaluation of Donors Aged 17–55 Years
Section snippets
Methods
In this retrospective study, we reviewed clinical records of 1084 consecutively performed DMEKs for endothelial pathologies between July 1, 2011 and November 30, 2015 at the Department of Ophthalmology, University of Cologne, Cologne, Germany. The data have been prospectively compiled within the Cologne DMEK database, using REDCap electronic data capture tools. REDCap (Research Electronic Data Capture) is a secure, web-based application designed to support data capture for research studies.17
Results
Clinical records of 1084 consecutively performed DMEKs in eyes with endothelial pathologies were reviewed; 529 cases (48.8%) met all inclusion and no exclusion criteria and were available for further analyses. Out of these 529 cases, 94 (17.8%) could be assigned to the young donor group (donor age ≤55 years), whereas 435 (82.2%) could be assigned to the old donor group (>55 years).
Discussion
Descemet membrane endothelial keratoplasty has become the superior form of endothelial keratoplasty in routine cases of corneal endothelial diseases in several countries worldwide. Despite obvious advantages over DSAEK, such as less graft rejection and faster visual recovery, graft preparation was suggested to be one of the most important technical limitations of DMEK.8, 21, 22 Donor tissue characteristics that contribute to major complications of donor preparation or graft implantation, such
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