Original articleOptical Coherence Tomography Angiography Quantitative Assessment of Choriocapillaris Blood Flow in Central Serous Chorioretinopathy
Section snippets
Methods
An international review board approval (French Society of Ophthalmology) was obtained for this study and all the investigations adhered to the tenets of the Declaration of Helsinki. All patients included in this study provided fully informed consent before participation.
This case-control study included naïve consecutive patients with acute, recurrent, or persistent forms of CSC, referred to the Croix-Rousse University Hospital Retinal Center between July 8, 2016 and September 8, 2017. The
Results
Sixty patients with CSC and 60 healthy control subjects were included in this study. Each group consisted of 47 men and 13 women. Mean age was similar in both CSC patients and healthy individuals (42.9 ± 9.1 years vs 42.8 ± 8.8 years; P = .37). Among the CSC patients, 13.3% had a cardiovascular history (arterial hypertension [n = 7] and type 2 diabetes [n = 3]), while 26.7% were exposed to corticosteroid medication. Mean follow-up duration of CSC patients was 4.1 ± 3.1 months. A majority of
Discussion
Optical coherence tomography angiography is a recent noninvasive imaging technique providing high-resolution 3D reconstructions of retinal and choroidal vascular flow patterns. This study took advantage of detailed OCTA microvasculature assessment to analyze and quantify areas of flow reduction at the choriocapillaris level in CSC patients and age-matched healthy individuals. A substantial prospective cohort was achieved, relative to the incidence of CSC in general population,11 as a result of
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