Arrhythmias and conduction disturbanceFrequency of Recurrence of Atrial Fibrillation Within 48 Hours After Ablation and Its Impact on Long-Term Outcome
Section snippets
Patients
The present study was performed in 234 patients undergoing catheter ablation of either symptomatic drug-resistant paroxysmal or persistent AF. Type of AF was defined according to generally accepted guidelines.1 Baseline characteristics of the study population are listed in Table 1. Patients with paroxysmal AF were stratified into 4 groups according to the frequency of AF episodes per month (Table 1).
Preablation treatment
Adequate oral or subcutaneous anticoagulation therapy was given for ≥1 month before the
Results
A total of 234 patients with either paroxysmal (n = 165) or persistent (n = 69) AF were included in the study and underwent either a Lasso catheter-guided or CARTO-guided ablation procedure (Table 1). Compared with the CARTO-guided procedure, the Lasso approach had significantly shorter radiofrequency energy application time (22 ± 11 vs 32 ± 10 minutes; p <0.001), significantly longer fluoroscopic duration (64 ± 18 vs 46 ± 18 minutes; p <0.001), and significantly longer procedure duration (173
Discussion
In the present study, recurrence of AF within the first 48 hours after AF ablation could be identified as a significant predictor of adverse long-term ablation outcome in both univariate and multivariate analyses. This was true not only for the entire study population, but also for subgroups of patients with paroxysmal and persistent AF and patients undergoing a Lasso- or CARTO-guided ablation approach. If AF occurred within the first 2 days after ablation, the independent risk of long-term
Acknowledgment
The authors thank Christina Zeilinger for great support.
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