Preventive cardiologyRelation of Childhood Risk Factors to Left Ventricular Hypertrophy (Eccentric or Concentric) in Relatively Young Adulthood (from the Bogalusa Heart Study)
Section snippets
Methods
The Bogalusa Heart Study was a long-term epidemiologic study of the early natural history of arteriosclerosis in children and young adults from a semirural biethnic (65% white, 35% black) community in Bogalusa, Louisiana.1 As a part of a longitudinal cohort survey, echocardiographic examinations of the heart were performed from 2000 to 2002. Eight hundred twenty-four eligible black and white adult subjects (age range 24 to 44 years, average 36; 41% men, 69% white) who had CV risk-factor
Results
As listed in Table 1, in this study cohort of 824 young adults, the prevalence of echocardiographic LV hypertrophy was 6.6%. Eccentric LV hypertrophy was present in 4.7%; concentric LV hypertrophy, in 1.8%; and concentric remodeling, in 4.7%. A total of 7.4% of men had concentric remodeling compared with 2.9% of women (p <0.01). Blacks had a significantly higher prevalence of eccentric (7.4%) and concentric LV hypertrophy (3.5%) compared with whites (3.5% and 1.1%, respectively). Subjects with
Discussion
The prevalence of echocardiographic LV hypertrophy was 6.6% in our biracial community-based sample of healthy young adults. We observed that eccentric LV hypertrophy (72% of LV hypertrophy) was more frequent than concentric LV hypertrophy, and black subjects had more LV hypertrophy than whites. BMI in both adulthood and childhood was a significant determinant of eccentric LV hypertrophy. Concentric LV hypertrophy was related to diabetes mellitus status in adulthood and diastolic blood pressure
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