MiscellaneousContemporary Features, Risk Factors, and Prognosis of the Post-Pericardiotomy Syndrome
Section snippets
Methods
The study population consisted of 360 consecutive patients enrolled at 6 general hospitals from urban areas of Italy (Maria Vittoria Hospital, Turin; Ospedali Riuniti, Bergamo; Mauriziano Hospital, Turin; Niguarda Hospital, Milan; San Maurizio Regional Hospital, Bolzano; and Ospedale Degli Infermi, Rivoli). All patients were adults and candidates for cardiac surgery for any reason, including coronary artery bypass grafting, valvular diseases, congenital heart disease, or aortic disease. The
Results
PPS was diagnosed in 54 of 360 patients (15.0%) <12 months after cardiac surgery. The time course of PPS occurrence was as follows: 28 cases (51.9%) in week 1, 9 cases (16.7%) in week 2, 4 cases (7.4%) in week 3, and 2 cases (3.7%) in week 4. Most cases occurred in the first month (79.6%), while the remaining cases were all confined to the first 3 months after cardiac surgery: 7 (13.0%) during the second month and 4 (7.4%) in the third month after cardiac surgery (Figure 1, Figure 2).
The mean
Discussion
In the present prospective study the incidence of the PPS was about 15% at 1 year after cardiac surgery. Nevertheless, all cases were confined to the first 3 months, and especially within the first month (about 80%), with a peak at the end of the first week (Figure 1). Such findings may be only partially consistent with a supposed autoimmune pathogenesis, suggesting the relevance of the surgical trauma per se, particularly in early cases. At the same time, the initial injury, which may involve
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