Congenital heart diseaseIncidence and Predictors of Sudden Cardiac Arrest in Adults With Congenital Heart Defects Repaired Before Adult Life
Section snippets
Methods
Clinical records of 3,197 patients referred to the adult CHD unit at La Paz University Hospital for cardiac evaluation from January 1990 through January 2010 were retrospectively evaluated. For the present study, 1,289 patients (40%) who had a reparative or palliative intervention for CHD at <20 years of age were identified. The study group included all patients who were followed serially at our institution with a clinical visit within the previous 2 years or before an end point. A
Results
In total 936 patients (73%) were eligible for inclusion and comprised the study population. Distribution of diagnostic categories and duration of follow-up for the entire sample and separately by CHD category are presented in Table 1. Although the mean follow-up period ranged from 5 ± 5 years in patients with atrial septal defects to 11 ± 8 years in patients with repaired aortic stenosis, differences in follow-up were not statistically significant between diagnostic categories. Further details
Discussion
To our knowledge, this is the first longitudinal cohort study to analyze predictors of SCA in a large population of adult survivors after operation for CHD at <20 years of age. Results indicated that severe systemic ventricular dysfunction has an outstanding role as a dominant multivariate predictor of SCA for all combined diagnoses in this heterogenous population.
Until recently, limited data existed on risk factors for SCA during long-term follow-up after surgery in the total adult CHD
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