Clinical research studyThe Impact of the Aging Population on Coronary Heart Disease in the United States
Section snippets
The Coronary Heart Disease Policy Model
The Coronary Heart Disease Policy Model is a validated state-transition (Markov) model of the incidence, prevalence, mortality, and cost of coronary heart disease in US residents 35 to 84 years of age.4 The model has 3 components. First, the demographic-epidemiologic submodel estimates the incidence of coronary heart disease (cardiac arrest, myocardial infarction, angina, or coronary heart disease death) and death from other causes, based on age, sex, systolic blood pressure, smoking,
Results
In 2010, an estimated 156 million adults 35 to 84 years of age will be living in the US. This population is expected to increase by 28% to 200 million in 2040. The 65- to 84-year-old population is expected to increase by 89% percent over this period because of the aging of baby boomers and their longer life expectancy. The increase in coronary heart disease will reflect this population growth: incidence, prevalence, mortality, and cost are all expected to increase monotonically over the next 30
Discussion
Unprecedented growth in the 65 years of age and older population in the United States is expected over the coming decades. This growth will result in a substantial increase in coronary heart disease incidence, prevalence, mortality, and cost. A quantitative estimate of the magnitude of this increase is essential information for stakeholders in the US health care system, including patients, providers, training organizations, hospitals, health plans, governments, and industry.35, 36 Despite
References (40)
- et al.
The effect of risk factor reductions between 1981 and 1990 on coronary heart disease incidence, prevalence, mortality and cost
J Am Coll Cardiol
(2001) - et al.
Coronary heart disease attributable to passive smoking: CHD Policy Model
Am J Prev Med
(2009) - et al.
Demographics and cardiology, 1950-2050
J Am Coll Cardiol
(2000) Trends in aging—United States and worldwide
MMWR Morb Mortal Wkly Rep
(2003)- et al.
Deaths: final data for 2006
Natl Vital Stat Rep
(2009) - et al.
Forecasting coronary heart disease incidence, mortality, and cost: the Coronary Heart Disease Policy Model
Am J Public Health
(1987) Cost-effectiveness perspectives in coronary heart disease
Am Heart J
(1990)- et al.
Expected gains in life expectancy from various coronary heart disease risk factor modifications
Circulation
(1991) - et al.
Relative impact of targeted versus populationwide cholesterol interventions on the incidence of coronary heart diseaseProjections of the Coronary Heart Disease Policy Model
Circulation
(1989)
Cost-effectiveness of cholesterol-lowering therapies according to selected patient characteristics
Ann Intern Med
Long-term cost-effectiveness of various initial monotherapies for mild to moderate hypertension
JAMA
Health and economic benefits of increased beta-blocker use following myocardial infarction
JAMA
Long-term impact of smoking cessation on the incidence of coronary heart disease
Am J Public Health
Cost-effectiveness of vitamin therapy to lower plasma homocysteine levels for the prevention of coronary heart disease: effect of grain fortification and beyond
JAMA
Adolescent overweight and future adult coronary heart disease
N Engl J Med
Comparing impact and cost-effectiveness of primary prevention strategies for lipid-lowering
Ann Intern Med
Projected effect of dietary salt reductions on future cardiovascular disease
N Engl J Med
Deaths for 358 selected causes, by 5-year age groups, race and sex: United States, 1999-2000
Framingham Heart Study CD-ROM
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2022, Surgical Clinics of North AmericaCitation Excerpt :10.9% of adults aged 45 or older and 17.0% of adults aged 65 or older are estimated to have CAD, and approximately 800,000 Americans suffer a myocardial infarction (MI) each year.2 CAD is a major source of health care costs, estimated at $126.2 billion in 2010 and expected to increase to more than $177 billion by 2040.3 Vast improvements in care have led to a steady decline in CAD deaths over the past several decades.4
Detection of Coronary Artery Disease Based on Clinical Phonocardiogram and Multiscale Attention Convolutional Compression Network
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Funding: Supported in part by the Swanson Family Fund, Tempe, Ariz, and a grant-in-aid from the American Heart Association Western States Affiliate, Burlingame, Calif. (09GRNT2060096). Dr. Odden is supported by a Ruth L. Kirschstein National Research Service Award (T32HP19025). Dr. Moran is supported by an NIH/NHLBI Mentored Career Development Award (K08HL089675) and an Empire Clinical Research Program award from New York State.
Conflict of Interest: None.
Authorship: All authors were involved in the design of the study, interpretation of data, and the writing of the manuscript. All authors have approved the final version.