Clinical ScienceIs a surgical approach justified for octogenarians with pancreatic carcinoma? Projecting surgical decision making for octogenarian patients
Section snippets
Patients
The diagnosis of pancreatic cancer was made initially after imaging and then confirmed by pathologic analysis. We retrospectively reviewed the surgical pathology database of the Kochi Health Sciences Center to identify patients who underwent resection for pancreatic neoplasms from March 2005 to December 2013. Clinical characteristics evaluated included age, sex, part of the tumor, tumor size, surgical procedures undertaken, and pathologic data. The Eastern Cooperative Oncology Group (ECOG)
Results
From March 2005 to December 2013, 194 consecutive patients with newly diagnosed, surgically curable pancreatic cancer were managed in the Department of Gastroenterological Surgery at Kochi Health Sciences Center. Preoperative characteristics are detailed in Table 1. Of these patients, 100 were men and 94 were women, ranging in age from 34 to 88 years (mean 70.2 years), with 34 patients (17.5%) aged 80 years or older. The mean age in the octogenarian group (83.1 ± 2.3 years; range 80 to 88) was
Comments
The overall survival curves were virtually identical in this study of pancreatic cancer patients in those younger than and older than 80 years, and no statistically significant disadvantage in 3- and 5-year disease-free survival was observed between the octogenarian and younger groups. Furthermore, excellent curative treatment was achieved by surgical resection for octogenarian patients with pancreatic cancer, with zero mortality in the octogenarian group and no significant increase in
Acknowledgment
This work was supported by Kochi Organization for Medical Reformation and Renewal grants.
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The authors declare no conflicts of interest.