OSA Symptoms Associated With and Predictive of Anxiety in Middle-Aged Men: Secondary Analysis of NHANES Data

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Abstract

Object

This population-based study examined obstructive sleep apnea (OSA) symptoms predictive of anxiety in middle-aged men.

Method

Secondary analyses were conducted on the National Health and Nutrition Examination Survey (NHANES) 2007–2008 data using weighted samples and complex sample analysis techniques (unweighted N = 1,217).

Findings

Nonrefreshing sleep (χ2 = 69.333, p < 0.001), excessive daytime sleepiness (χ2 = 47.766, p < 0.001), and sleep fragmentation (χ2 = 30.692, p < 0.001) were significantly associated with anxiety. Nonrefreshing sleep (OR 3.582, p < 0.001) and awakenings due to apneic episodes (OR 2.047, p = 0.001) were predictive of anxiety.

Conclusion

Comorbid anxiety and OSA symptoms are common and have implications for activities of daily living, social responsibilities, and quality of life. Screening for anxiety among men with OSA symptoms is recommended.

Section snippets

Method

Secondary data analysis was conducted using 1,217 subjects (weighted N = 47,995,518) from the 2007–2008 National Health and Nutrition Examination Survey (NHANES), a program of studies conducted by the National Center for Health Statistics (NCHS), a division of the Centers for Disease Control and Prevention (NCHS, 2013). NHANES is designed to assess the health and nutritional status of adults and children in the United States (US) and to determine the prevalence of major diseases and their risk

Results

The mean age of men in this NHANES sample was 52.31 (± 7.23) years. Most of the men had a level of education beyond high school (54.9%), reported an annual income of $20,000 or more (89.0%), had health insurance (82.5%), were married or living with someone (75.1%), and were White (71.8%) (Table 1). The most commonly reported OSA symptoms were snoring (68.7%), nocturia (24.1%), nonrefreshing sleep (22.5%), sleep fragmentation (18.6%), frequent awakenings due to apneic-related episodes (17.0%),

Discussion

This study supports previous findings that OSA symptoms are associated with anxiety, and reveals new findings that specific OSA symptoms (nonrefreshing sleep and frequent awakenings due to apneic episodes) are predictive of anxiety among middle-aged men. The findings in this population-based study are consistent with previously reported research, expanding it to highlight the prevalence and predictors of anxiety in the middle-aged male population with OSA symptoms. Anxiety was reported by 22.4%

Acknowledgment

The authors thank the Centers for Disease Control: National Center for Health Statistics for providing data. The authors express no conflicts of interest related to this research.

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