Original articleGeneral thoracicSalvage Lung Resection After Definitive Radiation (>59 Gy) for Non-Small Cell Lung Cancer: Surgical and Oncologic Outcomes
Section snippets
Data Collection
Institutional Review Board approval was granted by the University of Washington (UW) in December 2005, with waiver of individual consent. Potential cases were identified from the 1997 to 2005 case log of the Thoracic Surgical Division. The first consultation note by a thoracic surgeon was reviewed for all cases of pulmonary wedge resection, lobectomy, or pneumonectomy. Entry criteria included (1) histologic or cytologic diagnosis of NSCLC; (2) prior treatment of NSCLC with curative-intent
Patient Characteristics
The characteristics of the 24 patients are detailed in Table 1. In 23 of 24 patients, the initial staging and treatment occurred at another institution, and they were referred for consideration of salvage lung resection. Specifics of initial staging procedures were known in 23 of 24 patients. A surgeon participated in 9 of 23 (39%) staging evaluations, and in 4 patients the surgeon was certified by the American Board of Thoracic Surgery or its equivalent (44% of surgical evaluations and 17% of
Comment
Intergroup 0139, a randomized phase III comparison of definitive chemoradiation vs induction chemoradiation followed by operation, did not demonstrate a survival benefit to trimodality therapy in patients with resectable stage IIIA NSCLC [9]. Although planned trimodality therapy remains an accepted standard in certain cases, the optimal therapy for patients with N2 disease remains controversial. National guidelines recommend that patients with resectable, locally advanced NSCLC be treated with
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