Original articleGeneral thoracicOutcomes Assessment of the Surgical Management of Esophageal Cancer in Younger and Older Patients
Section snippets
Material and Methods
All patients undergoing esophagectomy for cancer between 1991 and 2011 had information prospectively entered into an Institutional Review Board approved database; individual consent for this study was waived as patient data were anonymized. All patients were presented at a multidisciplinary tumor board. Data collection comprised preoperative demographics including comorbidities and clinical stage as well as details of neoadjuvant therapy. Approach to clinical staging did vary during the study
Results
When all patients presenting to our institution with the diagnosis of esophageal cancer during the period of study were assessed, 44% of patients 50 years or less and 35.8% of patients greater than 50 years underwent resection and were therefore included in this assessment. In total, 493 patients underwent surgical resection of esophageal malignancy from 1991 to 2011. Fifty-eight (11.76%) of these patients were in the 50 or less age group, and 435 (88.24%) patients were in the greater than 50
Comment
Recent reports demonstrate an increase in esophageal malignancy in younger patients [18], which parallels the overall increase in adenocarcinoma seen worldwide. In the US National Cancer Statistics (2008), 14.4% of patients presenting with esophageal malignancy are under the age of 55 [19]. Previously, the concern regarding younger patients with esophageal cancer was a poorer prognosis due to a delay in presentation [6] or more aggressive tumor biology [7]. Previous literature on this subject
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