ReviewThe α2δ subunits of voltage-gated calcium channels☆
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Graphical abstract
Highlights
► This review discusses the α2δ subunits of voltage-gated calcium channels. ► The α2δ subunits are involved in calcium channel trafficking. ► The α2δ subunits also affect biophysical properties of calcium channel currents. ► The α2δ subunits are associated with several different pathologies.
Abbreviations
DHP
dihydropyridine
DRG
dorsal root ganglion
ER
endoplasmic reticulum
HVA
high-voltage activated
LVA
low voltage-activated
MIDAS
metal ion dependent adhesion site
VWA
von Willebrand factor-A
Keywords
Calcium channel
Auxiliary subunit
Electrophysiology
Alpha2delta
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This article is part of a Special Issue entitled: Calcium channels.
Copyright © 2012 Elsevier B.V.