Randomized trial of a patient-centered decision aid for promoting informed decisions about lung cancer screening: Implementation of a PCORI study protocol and lessons learned
Section snippets
Introduction and background
Lung cancer is the second most common cancer and the leading cause of cancer deaths in the U.S. [1]. Five-year survival rates are only about 16.6%, in part because many patients have advanced disease at the time of diagnosis [2]. Smoking is the most important risk factor for developing and dying from lung cancer and is thought to cause about 90% of all lung cancers in the U.S [1, 3].
In June 2011, the National Lung Screening Trial (NLST) published its primary finding where 20% fewer lung cancer
Study aim and hypotheses
The aim of this study is to compare a video-based decision aid to standard educational materials on quitline patients' preparation to make a decision about lung cancer screening. The goal of the video-based decision aid is to prepare patients to have a conversation with their primary care provider and not to sway patients to be for or against lung cancer screening. We hypothesized that high-risk smokers eligible for lung cancer screening who receive the decision aid would: a) be more prepared
State quitlines
Four quitline service providers covering 13 states participated in the study. Our initial quitline partnerships were with the Alabama Tobacco Quitline and Tennessee Tobacco Quitline operated by Information & Quality Healthcare, which prospectively and retrospectively recruited participants. Then we expanded to the New York State Smokers' Quitline run by Roswell Park Cancer Institute. They had additional resources, which enabled us to send the recruitment materials directly to the state tobacco
Lessons learned
There were many lessons learned regarding working with state tobacco quitlines and high-risk smokers (Table 1). By working closely with our states and quitline service providers to get their input on realistic roles and expectations for the project, we were able to meet the needs of states and quitline service providers. As a result, we tailored study procedures for each state or quitline service provider. It also made it easier for us to expand our efforts to multiple states when the quitline
Acknowledgements
The authors would like to thank Vincent Richards, Andrea Palmieri Hempstead, and Rhodrick Harralson for data collection.
Ethics, consent, and permissions
This study was approved by the University of Texas MD Anderson Cancer Center Institutional Review Board [IRB APPROVAL 2014-0628].
Funding
This work was supported through a Patient-Centered Outcomes Research Institute (PCORI) Award (CER-1306-03385), the NIH/NCI under award number P30CA016672 and used the Biostatistics Resource Group and Clinical Protocal and Data Management, and The University of Texas MD Anderson Cancer CenterDuncan Family Institute for Cancer Prevention and Risk Assessment. All statements in this article, including its findings and conclusions, are solely those of the authors and do not necessarily represent the
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He is currently retired.