Original article—liver, pancreas, and biliary tractPrevalence, Diagnosis, and Profile of Autoimmune Pancreatitis Presenting with Features of Acute or Chronic Pancreatitis
Section snippets
Methods
The protocol was approved by the Mayo Clinic Institutional Review Board. We utilized a prospectively collected list of all patients presenting to the Mayo Pancreas Clinic for evaluation of acute or chronic pancreatitis between January 2005 and June 2006. We reviewed electronic medical records of all patients in this list to retrieve demographic, clinical, radiologic, and laboratory data and the final clinical diagnosis.
To investigate the clinical profile of AIP patients presenting with acute or
Prevalence of AIP Among Patients Evaluated for Acute or Chronic Pancreatitis
During the period January 2005 through June 2006, 178 patients (89 males [50%]) were evaluated at the Mayo Pancreas Clinic for possible acute or chronic pancreatitis. Of the 178 patients, the final clinical diagnosis was acute pancreatitis in 58 patients (32.6%), chronic pancreatitis in 79 patients (44.4%), benign or malignant tumor of the pancreas in 6 patients (3.4%), miscellaneous etiologies in 12 patients (6.7%), and no discernible disease of the pancreas in 16 patients (9%). Seven of 178
Discussion
Acute and chronic pancreatitis are considered to be uncommon clinical manifestations of AIP. In our study approximately 4% of patients evaluated for etiology of suspected pancreatitis had AIP based on HISORt criteria. We also reviewed the clinical profile of AIP patients diagnosed at our center from June 1999 through October 2008 to identify patients who had acute or chronic pancreatitis. We report that 24% of AIP patients had acute pancreatitis and 11% presented as chronic pancreatitis. In
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This article has an accompanying continuing medical education activity on page 3. Learning Objectives—Upon completion of this activity, the successful learner should be able to define the expected frequency, clinical features, and diagnostic criteria of autoimmune pancreatitis.
Conflict of interest The authors disclose no conflicts.