Original articleAlimentary tractMagnifying Chromoendoscopy and Endoscopic Ultrasonography Measure Invasion Depth of Early Stage Colorectal Cancer With Equal Accuracy on the Basis of a Prospective Trial
Section snippets
Patients
All patients who met all of the following inclusion criteria were prospectively enrolled in this study: (1) histologically confirmed adenocarcinoma by biopsy, including Category 4 or 5 of the Vienna classification18; (2) CRC diagnosed as early stage (within submucosal invasion) by conventional endoscopic observation; (3) flat lesions defined according to the Paris Workshop guidelines (type 0–IIa [slightly elevated], IIb [flat], IIc [slightly depressed])19; (4) tumor size ≤4 cm; (5) age 20–90
Patients
In total, 70 patients with 70 lesions were enrolled from February 2011 to December 2012 at 6 Japanese institutions, and 70 patients were randomly assigned, 36 patients to A group and 34 patients to B group. Each one lesion in both A and B groups that did not fulfill the study criteria and one lesion in B group for which observation was impossible were excluded. Moreover, one lesion in B group was excluded because histologic diagnosis of invasion depth was impossible because of the severe
Discussion
Recent technical developments such as ESD and laparoscopic surgery enable noninvasive treatment and provide many therapeutic options for CRC. Of the options, it is necessary to select an optimal therapeutic method depending on the status of each disease, and thus more accurate stage diagnosis is necessary before treatment. With respect to early CRC, because treatment differs completely depending on the presence or absence of deep submucosal invasion, it is important to distinguish M-SMS from SMD
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Diagnostic Value of Adding Magnifying Chromoendoscopy to Magnifying Narrow-Band Imaging Endoscopy for Colorectal Polyps
2023, Clinical Gastroenterology and HepatologyComputer-aided diagnosis system using only white-light endoscopy for the prediction of invasion depth in colorectal cancer
2021, Gastrointestinal EndoscopyCitation Excerpt :Currently, NBI, M-NBI, and MCE have exhibited high accuracy in diagnosing the invasion depth of CRC and should be considered as the standard criteria. The reported accuracy for diagnosing the invasion depth of CRC was 76.4% to 98.8%.8-12,15-18 EUS has also been used to diagnose the invasion depth of CRC, and its accuracy is reported to be 89.0%.19
Artificial intelligence for magnifying endoscopy, endocytoscopy, and confocal laser endomicroscopy of the colorectum
2020, Techniques and Innovations in Gastrointestinal EndoscopyCitation Excerpt :The authors constructed a CAD model based on a classical hand-crafted algorithm and evaluated its performance using 121 images from 121 lesions. Its achieved 84% sensitivity and 83% specificity in discriminating SM-m, which were considered excellent values given even expert endoscopists reportedly achieve only 74% sensitivity and 69% specificity in identifying such lesions [21]. Recently, 2 research teams conducted retrospective studies on newly developed CAD systems based on a deep-learning (convolutional neural network) algorithm.
Conflicts of interest The authors disclose no conflicts.