Cancer metastasis as a therapeutic target

https://doi.org/10.1016/j.ejca.2010.02.039Get rights and content

Abstract

Despite many years of basic and clinical research aimed at curbing tumour growth, metastasis remains the prime reason why cancer patients succumb to their disease. Effective translational research is urgently required, yet is not always easy to achieve. Here we review reasons why metastasis as a disease process has proven difficult to control, and suggest ways in which translational research in this area can be strengthened and advanced.

Section snippets

Conflict of interest statement

None declared.

Acknowledgements

J.P.S. gratefully acknowledges funding from the European Union under the auspices of the FP7 collaborative project TuMIC, Contract No. HEALTH-F2-2008-201662. P.S.S. is supported by the Intramural Program of the National Cancer Institute, USA.

Cited by (0)

View full text