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The EQ-5D: A useful quality of life measure in borderline personality disorder?

Published online by Cambridge University Press:  16 April 2020

A.D.I. van Asselt ,
C.D. Dirksen ,
A. Arntz ,
J.H. Giesen-Bloo  and
J.L. Severens
A.D.I. van Asselt*
Affiliation:
Department Of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Center, P.O. Box 5800, 6202AZMaastricht, The Netherlands
C.D. Dirksen
Affiliation:
Department Of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Center, P.O. Box 5800, 6202AZMaastricht, The Netherlands
A. Arntz
Affiliation:
Department of Clinical Psychological Science, Maastricht University, P.O. Box 616, 6200MDMaastricht, The Netherlands
J.H. Giesen-Bloo
Affiliation:
Department of Clinical Psychological Science, Maastricht University, P.O. Box 616, 6200MDMaastricht, The Netherlands
J.L. Severens
Affiliation:
Department Of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Center, P.O. Box 5800, 6202AZMaastricht, The Netherlands Department of Health Organization, Politics and Economics, Maastricht University, P.O. Box 616, 6200MDMaastricht, The Netherlands
*
*Corresponding author. University Hospital Maastricht, Department of KEMTA, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands. Tel.: +31 43 3875587; fax: +31 43 3874419. E-mail address: thea.van.asselt@mumc.nl (A. D. I. Van Asselt).
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Abstract

Introduction

Borderline Personality Disorder (BPD) is a severe psychiatric disorder and is associated with significant impairment in quality of life. The aim of the present study is to assess the internal and external responsiveness of the EuroQoL-5D (EQ-5D) in BPD patients.

Patients and Methods

Data from 49 patients included in a multi-center Dutch randomized trial were used. We used both the EQ-5D utility score and the Visual Analogue Scale of the EuroQoL, and the Borderline Personality Disorder Severity Index-IV (BPDSI-IV). To determine internal responsiveness, we calculated the standardized response mean (SRM). To determine external responsiveness, we calculated Spearman correlations for the change scores, and compared EQ-5D scores for clinically improved vs. non-clinically improved patients as measured with the BPDSI-IV.

Results

Patient scores improved on all instruments during the three years. SRMs for BPDSI-IV were significantly higher than EQ-5D utility. Three-year Spearman correlation between change scores of BPDSI-IV and EQ-5D utility was 0.487, between BPDSI-IV and EQ-VAS it was 0.404, both statistically significant. EQ-5D utility scores for patients who clinically improved were significantly higher than for patients who did not.

Discussion

We conclude that the EQ-5D is fairly responsive in BPD, and, therefore, especially because of its brevity and user-friendliness, can serve as a useful tool in economic evaluations in patients with BPD.

Keywords

Borderline Personality DisorderHealth economicsQuality of life
Type
Original article
Information
European Psychiatry , Volume 24 , Issue 2 , March 2009 , pp. 79 - 85
Copyright
Copyright © Elsevier Masson SAS 2009

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