Elsevier

EXPLORE

Volume 6, Issue 5, September–October 2010, Pages 295-307
EXPLORE

Clinical article
Hypothesis
Nonlocality, Intention, and Observer Effects in Healing Studies: Laying a Foundation for the Future

https://doi.org/10.1016/j.explore.2010.06.011Get rights and content

All research domains are based upon epistemological assumptions. Periodic reassessment of these assumptions is crucial because they influence how we interpret experimental outcomes. Perhaps nowhere is this reassessment needed more than in the study of prayer and intention experiments. For if positive results from this field of research are sustained, the reality of nonlocal consciousness must be confronted. This paper explores the current status of healing and intention research, citing a number of major studies and using the “Study of the Therapeutic Effects of Intercessory Prayer (STEP) in Cardiac Bypass Surgery Patients: A Multicenter Randomized Trial of Uncertainty and Certainty of Receiving Intercessory Prayer” as a case study of this line of research. The paper argues that the dose-dependent model typical of drug trials, and adopted for use in the STEP and other studies, is not the optimal model for intention-healing research, and critiques this approach in detail, citing apposite research from which we draw our recommendations and conclusions. The paper suggests that the usual assumptions concerning blindness and randomization that prevail in studies using the pharmacological model must be reappraised. Experimental data suggest that a nonlocal relationship exists among the various individuals participating in a study, one which needs to be understood and taken seriously. We argue that it is important to account for and understand the role of both local and nonlocal observer effects, since both can significantly affect outcome. Research is presented from an array of disciplines to support why the authors feel these issues of linkage, belief, and intention are so important to a successful, accurate, and meaningful study outcome. Finally, the paper offers suggestions for new lines of research and new protocol designs that address these observer-effect issues, particularly the nonlocal aspects. The paper finally suggests that if these effects occur in intention studies, they must necessarily exist in all studies, although in pharmacological studies they are often overshadowed by the power of chemical and biological agents.

Introduction

Epistemologically periodically reassessing what constitutes good research is crucial because this process gives us the ability to distinguish justified belief from opinion. Perhaps nowhere is this distinction of greater significance than in the study of prayer and intention experiments. For if the positive results from this field of research are sustained, the reality of nonlocal consciousness must be taken seriously. This paper explores the current status of healing and intention research, cites a number of major studies, and uses the “Study of the Therapeutic Effects of Intercessory Prayer (STEP) in Cardiac Bypass Surgery Patients: A Multicenter Randomized Trial of Uncertainty and Certainty of Receiving Intercessory Prayer” conducted by Herbert Benson et al1 as a case study of this line of research. In April 2006, researchers from Harvard Medical School published this long-awaited study in the American Heart Journal.1 The $2.4 million study was funded in large part by the John Templeton Foundation, which promotes the study of the intersection of religion and science. Its publication grabbed headlines across America for two main reasons: it originated from Harvard Medical School, and it had an unexpected result—patients who were prayed for, and knew they would be prayed for, fared the worst of the three intervention groups.

Because of its venue, its level of funding, and the media attention the study has engendered, we have selected this study as a case demonstrating issues common to much of this research field, and we use it to explore those issues. In the process, we also examine attitudes that prevail in the arguments of both proponents and skeptics of prayer and intention research. What we seek is a discussion on the basic assumptions implicit, but usually unacknowledged, in these studies, and a reappraisal of the design parameters upon which prayer and intention studies have been grounded. In our view, STEP is a noble failure; noble because it was done with integrity, on the basis of imperfect understanding, and because its failure has much to teach us.

Section snippets

Step Background

The STEP experiment involved 1,802 patients undergoing coronary artery bypass surgery at six US hospitals.1 These 1,802 patients were then assigned to one of three subpopulations. Therapeutic intention in the form of prayer was provided by one Protestant and two Catholic groups, whose members were told to pray for a quick recovery with no complications. They were provided only with the first name and the initial of the last name of the prayer participants—“John D.” Prayers were initiated on the

Observer-Expectancy Effects, Both Local and Nonlocal

The randomized, double-blind clinical trial is widely considered the gold standard of judging the efficacy of any therapy. If a study is adequately randomized and blinded, it is assumed that the effects of belief, intention, and conviction of subjects and researchers are bypassed. Applying this logic to prayer experiments, it is assumed that what an experimenter privately thinks about the intercession is irrelevant. Yet experimental results suggest it is not that simple.

Rather, data suggest

The Question of Time

Nonlocality also opens another consideration important to understanding intention/prayer studies: the issue of time.

Consider the retroactive intercessory prayer study carried out by Israeli immunologist Leonard Leibovici.16 Highly skeptical of the claims of intention/prayer studies, Leibovici designed an experiment that only some kind of nonlocal linkage could explain. The very idea of such an effect challenges many assumptions. Yet retrocausality has become an area of intense research. The

Dosage

The STEP study required prayer for only 14 days. Is a two-week intervention an adequate test of prayer? What about the duration of each prayer session? One positive prayer study required an hour of prayer19; one failed study required five minutes.20 Is duration the determinant factor here? Many studies do not even consider this issue. What is the requisite dosage of therapeutic intention? Does this question even make sense given the nonlocal nature of the effect? We are aware of only one study,

Blindness and Randomization

For over 30 years, research has suggested that both randomization and blindness do not perform the same functions in experiments involving nonlocal perception or perturbation, of which intention/prayer studies are a subcategory, as they are assumed to do in drug trials. The literature supporting this conclusion is now so large that we will simply mention three studies: two involving perception—remote viewing and Ganzfeld protocol studies—and perturbation—direct mental interactions with living

Agent of Action

One of the most pressing questions future intention research must consider is who is the agent of action? Is there only one? What would the effect be if all the participants were somehow linked—or there are no such linkages at all? Positive prior studies suggest that something nonlocal is happening, but exactly what? Are the results achieved because of a person's therapeutic intention? Or is the outcome determined by the beliefs of the person who is the overt focus of the intention? Or, even

Can Prayer Harm?

Biologist Carroll Nash of St. Joseph's College, Philadelphia, carried out a therapeutic intention study involving bacterial colonies, cultured in common, and then split into three independent subpopulations.39 His purpose was to replicate earlier studies by nun and biochemist Sister Justa Smith40 and nursing pioneer Dolores Krieger,41 who along with Dora Kunz would later develop the nonsectarian approach to therapeutic intent known as Therapeutic Touch. Smith's studies had shown significant

Healers, Rituals, and Prayers

We know very little about what qualifies a person to successfully express therapeutic intention as a healer. Most investigators believe that the sincerity and genuineness of prayer must surely make a difference, but in most prayer experiments these factors are merely assumed without being rigorously assessed. In contrast, the skills of the cardiac surgeons in the STEP study were not assumed; the surgeons had met stringent objective requirements that qualified them for their role.

Evidence Ignored

To place the STEP study in context, one would expect that critics and analysts would cite and compare it with earlier prayer studies that reported positive outcomes. This has not happened. Study of the Therapeutic Effects of Intercessory Prayer has become such a marked feature of the healing intention debate that it often goes unchallenged and is assumed to be the final word. This seems an undeniable bias—a position counter to accepting science's fundamental commitment to go where sound data

How to do a Prayer Study

Four months before the Harvard study was published, mind-body researcher Jeanne Achterberg, a veteran explorer of indigenous healing methods and the role of imagery and visualization in healthcare, published an experiment incorporating many of the propositions we raise here.67 The work of Achterberg and her team was ignored by the nation's media which, we believe, was a shame, because it is the kind of next-generation study needed if we are to more fully understand the effects of intention.

The Future

Therapeutic intention expressed through prayer is now and always has been a universal human activity. We wear different clothes. Speak different languages. Eat different foods, spiced by different condiments, consumed using different implements. We worship different Gods, with different rituals. But the overwhelming majority of us not only believe but operationalize some way of opening ourselves to a greater whole to express therapeutic intention. We pray. Individuals or minority cohorts may

Acknowledgments

The authors thank William Braud, PhD, Dean Radin, PhD, and Vernon Neppe, MD, PhD, for their critical review, comments, and suggestions concerning our paper.

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