In vitro culture under physiologic oxygen concentration improves blastocyst yield and quality: a prospective randomized survey on sibling oocytes

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A prospective randomized study was carried on sibling oocytes in which human gametes and embryos were cultured at physiologic (6% CO2 + 5% O2 + 89% N2) condition from insemination to day 6 or at atmospheric (6% CO2 in air) condition until day 3 and at physiologic environment afterward. The results showed that physiologic oxygen concentration throughout culture period improved total blastocyst yield and day5 embryo quality.

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H.N.C. has nothing to declare. T.A. has nothing to declare. K.Y. has nothing to declare. I.K. has nothing to declare; M.B. has nothing to declare.

Data accepted for poster presentation at the 22nd Annual Meeting of the European Society for Human Reproduction and Embryology (ESHRE), Barcelona, Spain, July 2008.