Elsevier

Fertility and Sterility

Volume 93, Issue 1, 1 January 2010, Pages 96-100
Fertility and Sterility

In vitro fertilization
Comparison of in vitro fertilization versus intracytoplasmic sperm injection in extremely low oocyte retrieval cycles

https://doi.org/10.1016/j.fertnstert.2008.09.039Get rights and content
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Objective

To compare the results of IVF and intracytoplasmic sperm injection (ICSI) in extremely low oocyte retrieval cycles.

Design

Case–control study.

Setting

An IVF laboratory in a university hospital in Taiwan.

Patient(s)

Between January 2003 and December 2007, infertile couples with one, two, or three oocytes per retrieval were divided into two groups: 56 IVF cycles based on 28 demographic characteristics from the ICSI group.

Intervention(s)

None.

Main Outcome Measure(s)

Fertilization rate, cycle cancellation rate, clinical pregnancy rate, and implantation rate per transfer.

Result(s)

The normal fertilization rate was significantly higher after ICSI than after standard IVF (86.4% vs. 69.3%). The cycle cancellation and complete fertilization failure rates were comparable between the two groups. The clinical pregnancy rate per transfer (38.5% vs. 21.6%), implantation rate (23.5% vs. 11.1%), and live birth rate per transfer (30.8% vs. 13.7%) had a favorable trend, but no statistically significant differences, in the ICSI group compared with the IVF group.

Conclusion(s)

A higher normal fertilization rate can be achieved by ICSI in comparison with conventional IVF in extremely low oocyte retrieval cycles.

Key Words

IVF
ICSI
poor responder
oocyte number

Cited by (0)

Y.-C.O. has nothing to disclose. K.-C.L. has nothing to disclose. F.-J.H. has nothing to disclose. F.-T.K. has nothing to disclose. T.-H.L. has nothing to disclose. S.Y.C. has nothing to disclose.

Supported in part by grants CMRPG870091 from Chang Gung Memorial Hospital and NMRPG860101 from the National Science Council of Taiwan.