Original articleClinical endoscopyNarrow-band imaging colonoscopy—a pilot feasibility study for the detection of polyps and correlation of surface patterns with polyp histologic diagnosis
Section snippets
Study population
This study was conducted at the Kansas City Veterans' Affairs Medical Center and was approved by the local Institutional Review Board. Patients referred to the GI endoscopy unit for screening colonoscopy were enrolled in the study, and informed consent was obtained from all subjects. Inclusion criteria were average-risk screening for colon cancer and ability to provide written, informed consent. The exclusion criteria were prior surgical resection of any portion of the colon, inflammatory bowel
Patients
A total of 40 patients were prospectively enrolled and all completed the study. The mean age was 62 ± 9.5 years, all men. This included 32 whites, 7 blacks, and 1 Hispanic. All patients were undergoing average-risk screening for colorectal cancer with no prior history of colon polyps or cancer. The procedures (ie, both WLC and NBI) were completed in all, and the cecum was successfully intubated in every patient. Quality of the preparation was good in all examinations, and visualization of the
Discussion
Colonoscopy is the preferred and a widely used method for the detection and removal of colon polyps. Initial studies demonstrated that colonoscopy with polypectomy could prevent 76% to 90% of incident colorectal cancers.4, 10, 11 However, recent evidence involving cohorts of patients with tubular adenomas reveals that the incidence of colon cancer after a clearing colonoscopy is in fact higher than previously reported.12, 13, 14 Several factors have been implicated in the development of colon
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Improvement in the visibility of colorectal polyps by using blue laser imaging (with video)
2015, Gastrointestinal EndoscopyHigh-resolution microendoscopy in differentiating neoplastic from non-neoplastic colorectal polyps
2015, Best Practice and Research: Clinical GastroenterologyMethods to become a high performer in characterization of colorectal polyp histology
2015, Best Practice and Research: Clinical GastroenterologyTools for polyp histology prediction
2015, Gastrointestinal Endoscopy Clinics of North AmericaCitation Excerpt :Two patterns were described for hyperplastic polyps and 2 for adenomas (Fig. 3, Table 3).30,31 These results showed a sensitivity, specificity, and accuracy of 96%, 89%, and 93%, respectively, for polyp histology prediction.30 A similar classification was described by Rex32 that showed an accuracy of 89% for characterizing adenomas.