Original contributionsSurgical pathology of infected aneurysms of the descending thoracic and abdominal aorta: Clinicopathologic correlations in 29 cases (1976 to 1999)
Section snippets
Patient selection
The study design was approved by the Mayo Foundation Institutional Review Board. All patients who had undergone aortic reconstruction for aneurysms distal to the left subclavian artery between January 1, 1976 and December 31, 1999 were identified retrospectively in the surgical database of Mayo Clinic Rochester. Patients were defined as having infective aortitis based on clinical evidence of infection, such as fever, pain, and leukocytosis; operative findings of aortic inflammation and
Demographic findings
During the study period, 6137 patients underwent aortic reconstruction for thoracic and abdominal aneurysms. Of these patients, 43 (0.7%) fulfilled the criteria for infected aneurysms. Detailed clinical and surgical outcomes for these patients have been reported earlier. 13
From these 43 patients, our study group included the 29 patients for whom archived slides or tissue specimens were available for review. The group comprised 23 men (79%) and 6 women (21%), ranging in age from 46 to 86 years
Discussion
Infected aneurysms of the descending thoracic or abdominal aorta are rare. Here we discuss 5 topics in light of the findings of the present study: pathogenesis, risk factors for aortic infection, culture results, infecting organisms, and microscopic features.
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