Discussion of the role of immunomodulatory agents to reduce the cytokine storm in severe cases of COVID-19.
•
Potential immunomodulatory agents currently used in the treatment of COVID-19 (chloroquine, hydroxychloroquine and tocilizumab) are discussed.
•
Other immunomodulatory agents with good safety profiles may be considered for use in combination with antiviral drugs for the treatment of severe or critical cases of COVID-19.