Cytokine storm and immunomodulatory therapy in COVID-19: Role of chloroquine and anti-IL-6 monoclonal antibodies

https://doi.org/10.1016/j.ijantimicag.2020.105982Get rights and content

Highlights

  • Discussion of the role of immunomodulatory agents to reduce the cytokine storm in severe cases of COVID-19.

  • Potential immunomodulatory agents currently used in the treatment of COVID-19 (chloroquine, hydroxychloroquine and tocilizumab) are discussed.

  • Other immunomodulatory agents with good safety profiles may be considered for use in combination with antiviral drugs for the treatment of severe or critical cases of COVID-19.

Keywords

COVID-19
Cytokine storm
Chloroquine
Hydroxychloroquine
Tocilizumab

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