International Journal of Oral and Maxillofacial Surgery
Clinical PaperOral SurgerySpontaneous bone healing of the large bone defects in the mandible
Section snippets
Materials and Methods
33 patients with large BDs after surgical treatment were included in the study, 14 males and 19 females, aged from 5 to 70 years. Predominant were patients with inflammatory odontogenic cysts (radicular and residual) followed by odontogenic keratocysts (15 radicular and 1 residual cysts, 13 odontogenic keratocysts, 2 follicular cysts, 1 ameloblastic fibroma and 1 eosinofil granuloma).
The patients were treated with standard enucleation or radical extended extirpation (cyst walls with part of the
Results
Clinical observations and visual subjective radiographic analysis showed that detectable spontaneous bone regeneration occurred in all patients. No patient had inflammatory or other complications.
Computer analysis of PRs showed that the mean gain of bone density was 7% after 2 months, 27% after 6 months and 46% after 1 year. The values of the indexes of relative bone healing of the observed BD regarding their size on radiographic projections are shown in Fig. 4, Fig. 5 summarizes data about
Discussion
Bone healing in the mandible of BDs 20–50 mm in diameter is better than the authors expected clinically. Computer analysis of PRs showed that the mean final bone density in the BDs was 88% of the bone density of the surrounding bone. In the cases of smaller BDs (20–30 mm) the final bone density was 97%, while BDs of 30–50 mm healed with 84% of normal surrounding bone density after 1 year. These results are similar to those reported by Chiapasco et al.5 despite using a different method. It means
References (25)
The time sequence of tissue regeneration in human extraction wounds
Oral Surg Oral Med Oral Pathol
(1969)- et al.
Modes of healing histologically after endodontic surgery in 70 cases
Int J Oral Surg
(1972) - et al.
The accurancy of an x-ray film quality-assurance step-wedge test
Oral Surg Oral Med Oral Pathol
(1986) - et al.
A comparison of maxillary and mandibular bone mineral densities
J Prost Dent
(1998) - et al.
Densitometric analysis of experimentally produced periapical radiolucencies
Oral Surg Oral Med Oral Pathol
(1977) - et al.
Alveolar Wound Healing and ridge Remodeling After Tooth Extraction in the Rat
J Oral Maxillofac Surg
(1985) - et al.
Repair of bone defects by applying biomatrices with and without autologous osteoblasts
J Cran Maxillofac Surg
(2005) - et al.
Incomplete Bone Healing of Experimental Cavities in Dog Mandibles
Br J Oral Surg
(1971) An evaluation of bone healing in cavities in the jaws implanted with collagen matrix
Brit J Oral Maxillofac Surg
(1992)- et al.
In vivo experimental study on bone regeneration in critical bone defects using an injectable biodegradable PLA/PGA copolymer
Oral Surg Oral Med oral Pathol Oral Radiol Endod
(2005)
Bone marrow stem cells and biological scaffold for bone repair in aging and disease
Mechanisms Ageing Development
Digital Subtraction Radiography for Detecting Cortical and Cancellous Bone changes in the Periapical Region
J Endod
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